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Citation
Brookheart, R.T., Duncan, J.G. (2016). Modeling dietary influences on offspring metabolic programming in Drosophila melanogaster.  Reproduction 152(3): R79--R90.
FlyBase ID
FBrf0233008
Publication Type
Review
Abstract
The influence of nutrition on offspring metabolism has become a hot topic in recent years owing to the growing prevalence of maternal and childhood obesity. Studies in mammals have identified several factors correlating with parental and early offspring dietary influences on progeny health; however, the molecular mechanisms that underlie these factors remain undiscovered. Mammalian metabolic tissues and pathways are heavily conserved in Drosophila melanogaster, making the fly an invaluable genetic model organism for studying metabolism. In this review, we discuss the metabolic similarities between mammals and Drosophila and present evidence supporting its use as an emerging model of metabolic programming.
PubMed ID
PubMed Central ID
PMC4964793 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Reproduction
    Title
    Reproduction
    Publication Year
    2001-
    ISBN/ISSN
    1470-1626
    Data From Reference