FlyBase Insertion Report: Dmel\P{Switch-unk}TIGS-2

General Information

Symbol

Dmel\P{Switch-unk}TIGS-2

Species

D. melanogaster

Name

FlyBase ID

FBti0128176

Feature type

transposable_element_insertion_site

Also Known As

TIGS-2, TIGS, GS-TIGS-GAL4

Description

Inserted Element

P{Switch-unk}

LINE ID

Affected gene(s)

Scer\GAL4

Viability / fertility

Associated allele(s)

Scer\GAL4^TIGS-2

Stock availability

None publicly available

Genomic Location

Chromosomal Location

Sequence Location

Target / Docking site

Member of Large Scale Dataset(s)

Dataset

Description

Detailed Mapping Data

Chromosome (arm)

Sequence Location

Orientation

Cytological location (computed by FlyBase)

Cytological location (reported)

Insertion into Natural transposon

Comments concerning location

Sequence Data

Flanking sequence

Inserted Element

Construct

P{Switch-unk}

(Poirier et al., 2008)

Size (Kb)

Component Allele(s)

Molecular map

Affected Gene(s)

Insertion may affect gene

Scer\GAL4

(Gendron and Pletcher, 2017, Kabil et al., 2011, Rera et al., 2011, Poirier et al., 2008)

Variant Molecular Consequences

Phenotypic Data

Associated Allele

Phenotypic Data

Scer\GAL4^TIGS-2

Phenotypic Class Phenotype Manifest in Detailed Description

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval fat body

(Yamashita et al., 2021)

larval digestive system

(Yamashita et al., 2021)

pupal stage -- adult stage

adult digestive system

(Rera et al., 2011)

adult stage

adult digestive system

(Poirier et al., 2008)

adult midgut

(Filer et al., 2017)

adult gut

(Yamashita et al., 2021)

Additional Information

Statement

Reference

Drives mifepristone-inducible expression in the larval, pupal, and adult digestive system, and in the larval fat body.

(FlyBase Curators, 2017)

ScerGAL4^TIGS-2 drives expression in the digestive tract, but not in the fat body.

(Rera et al., 2011)

ScerGAL4^TIGS-2 drives mifepristone-inducible expression in the pupal/adult digestive system.

(Poirier et al., 2008)

Marker for

adult digestive system

(Rera et al., 2011)

Reflects expression of

Reporter construct used in assay

Ecol\lacZ^UAS.cBa

(Poirier et al., 2008)

Data on Genetic Line

Line ID

Origin as a multiple insertion line

Progenitor(s) within the Genome

Related Aberration or Balancer

Aberration

Balancer

Stocks (0)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (15)

Reported As

Symbol Synonym

GAL4-TIGS

(Anver et al., 2024)

GS-TIGS-GAL4

(Gendron and Pletcher, 2017)

GS-TIGS2-GAL4

(Gendron and Pletcher, 2017)

GS-tigs-GAL4

(Pickering et al., 2017)

P{Switch-unk}TIGS-2

(FlyBase, 1992-)

TI-GeneSwitch

(Yamashita et al., 2021)

TI^GS

(Yamashita et al., 2021)

TIGS

(Mizutani et al., 2025, Ureña et al., 2024, Martínez Corrales et al., 2020, Filer et al., 2017, Alic et al., 2014)

TIGS-2

(Parkhitko et al., 2021, Bjedov et al., 2020, Parkhitko et al., 2020, Ulgherait et al., 2020, Filer et al., 2017, Tain et al., 2017, Tawo et al., 2017, Parkhitko et al., 2016, Kabil et al., 2011, Rera et al., 2011)

TIGS-2 Gene-Switch

(Poirier et al., 2008)

TIGS-GAL4

(Ulgherait et al., 2020)

TIGS2

(Lennicke et al., 2025)

Ti-GS

(Xu et al., 2025)

TiGS

(Zhang et al., 2024, Martínez Corrales et al., 2022, Bolukbasi et al., 2017)

Tigs-Gal4-GS

(Tain et al., 2017)

Name Synonyms

Secondary FlyBase IDs

References (25)

Report Sections

Open Close