Allele Dmel\Itp-r83A^ka901

General Information
Symbol	Dmel\Itp-r83A^ka901	Species	D. melanogaster
Name		FlyBase ID	FBal0156348
Feature type	allele	Associated gene	Dmel\Itp-r83A
Also Known As	itpr^ka901

Map ( GBrowse )
Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Joshi et al., 2004)
Mutations Mapped to the Genome

Type Location Additional Notes References point mutation 3R:1,363,712..1,363,726 comment=Amino acid replacement G to S. Unable to determine, based on author statement, which residue is mutated within this reference sequence span. evidence=experimental reported_na_change=G?A reported_pr_change=G2630S (Joshi et al., 2004)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Amino acid replacement: G2630S. Nucleotide substitution: G?A. (Joshi et al., 2004)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| partially \| cold sensitive (with Itp-r83A^wc361) (Joshi et al., 2004) viable (with Itp-r83A^ug3), with Itp-r83A^Scer\UAS.cVa, Scer\GAL4^arm.PS (Joshi et al., 2004)
Phenotype Manifest In

Detailed Description
	Statement Reference The majority of Itp-r83A^ug3/Itp-r83A^ka901 larvae die in the second instar, by 176-184 hours after egg laying. (Joshi et al., 2004)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Complements	Itp-r83A^90B.0 (Joshi et al., 2004) Itp-r83A⁰⁵⁶¹⁶ (Joshi et al., 2004) Itp-r83A^B4 (Joshi et al., 2004) Itp-r83A^XR12 (Joshi et al., 2004)
Rescued by	Itp-r83A^ka901/Itp-r83A^ug3 is rescued by Scer\GAL4^arm.PS/Itp-r83A^Scer\UAS.cVa (Joshi et al., 2004)
Partially rescued by	Itp-r83A^ka901/Itp-r83A^ug3 is partially rescued by Scer\GAL4^Ddc.PL/Itp-r83A^Scer\UAS.cVa (Joshi et al., 2004) Itp-r83A^ka901/Itp-r83A^ug3 is partially rescued by Scer\GAL4^dimm-929/Itp-r83A^Scer\UAS.cVa (Joshi et al., 2004) Itp-r83A^ka901/Itp-r83A^ug3 is partially rescued by Scer\GAL4^elav-C155/Itp-r83A^Scer\UAS.cVa (Joshi et al., 2004) Itp-r83A^ka901/Itp-r83A^ug3 is partially rescued by Scer\GAL4^pros.PMG/Itp-r83A^Scer\UAS.cVa (Joshi et al., 2004)
Not rescued by	Itp-r83A^ka901/Itp-r83A^ug3 is not rescued by Scer\GAL4^12.1/Itp-r83A^Scer\UAS.cVa (Joshi et al., 2004) Itp-r83A^ka901/Itp-r83A^ug3 is not rescued by Scer\GAL4^Cha.7.4/Itp-r83A^Scer\UAS.cVa (Joshi et al., 2004)
Comments
Stocks ( 1 )
Bloomington	30741 w^*; Itp-r83A^ka901/TM6B, Tb¹
Notes on Origin
Discoverer

Comments
	Allelic series: Itp-r83A^sv35 >= Itp-r83A^ka901 > Itp-r83A^sa54 >= Itp-r83A^ka1091 > Itp-r83A^wc703 > Itp-r83A^ug3 > Itp-r83A^wc361. (Joshi et al., 2004)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Itp-r83A^ka901 itpr^ka901 (Srikanth et al., 2004, Kain et al., 2008) ka901 (Joshi et al., 2004)
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Kain et al., 2008, J. Neurosci. 28(18): 4745--4755 Reduced odor responses from antennal neurons of G(q)alpha, phospholipase Cbeta, and rdgA mutants in Drosophila support a role for a phospholipid intermediate in insect olfactory transduction. [FBrf0204625] Joshi et al., 2004, Genetics 166(1): 225--236 Genetic dissection of itpr gene function reveals a vital requirement in aminergic cells of Drosophila larvae. [FBrf0174703] Srikanth et al., 2004, Biophys. J. 86(6): 3634--3646 Functional properties of the Drosophila melanogaster inositol 1,4,5-trisphosphate receptor mutants. [FBrf0179452]

Allele Dmel\Itp-r83Aka901

Allele Dmel\Itp-r83A^ka901