Allele Dmel\smo5A.Scer\UAS.T:Zzzz\FLAG
| General Information | |||
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| Symbol | Dmel\smo5A.Scer\UAS.T:Zzzz\FLAG | Species | D. melanogaster |
| Name | FlyBase ID | FBal0177836 | |
| Feature type | allele | Associated gene | Dmel\smo |
| Allele class | |||
| Mutagen | in vitro construct - regulatory fusion, in vitro construct - coding region fusion, in vitro construct - amino acid replacement, in vitro construct - site directed mutagenesis | ||
Recent Updates
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| Description |
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| FB2013_03 | |||
| FB2013_02 | |||
| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
Nature of the Allele
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| Allele class | |||
| Mutagen | |||
| Mutations Mapped to the Genome | |||
Type Location Additional Notes References | |||
| Associated Sequence Data | |||
| DDBJ
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EMBL / GenBank | DNA sequence Protein sequence Name | ||
| UniProtKB/Swiss-Prot | |||
| UniProtKB/TrEMBL | |||
| Progenitor genotype | |||
| Nature of the lesion | Statement Reference Construct: Amino acid replacement: S667A. Amino acid replacement: S687A. Amino acid replacement: S740A. Amino acid replacement: T755A. Amino acid replacement: T785A. Nucleotide substitution: T2237G. Nucleotide substitution: T2287G. Nucleotide substitution: A2368G. Nucleotide substitution: G2369C. Nucleotide substitution: A2501A. Nucleotide substitution: A2539G. Scer\UAS regulatory sequences drive expression of a mutated form of smo in which the five putative PKA phosphorylation sites in the C-terminal, cytoplasmic tail have been mutated. The smo protein is tagged with T:Zzzz\FLAG at the C-terminal end. | ||
| Carried in construct | |||
| Tagged with | |||
| Cytology | |||
Phenotypic Data
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Phenotypic Class
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Phenotype Manifest In
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wing, with Scer\GAL4C-765 | |||
Detailed Description
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Statement Reference Expression of smo5A.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4C-765 results in a reduction in the distance between veins III and IV in the wing and a partial fusions of these veins proximal to the anterior crossvein. The reduction in distance between wing veins III and IV and partial fusions of these veins proximal to the anterior crossvein that is seen in flies expressing smo5A.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4C-765 are strongly enhanced by smo3/+. | |||
External Data
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| Linkouts | |||
Interactions
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Phenotypic Class
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Enhanced by | |||
Statement Reference | |||
Suppressed by | |||
Statement Reference Scer\GAL4C-765, smo5A.Scer\UAS.T:Zzzz\FLAG has visible phenotype, suppressible | partially by Scer\GAL4C-765/swm37Dh-1 Scer\GAL4C-765, smo5A.Scer\UAS.T:Zzzz\FLAG has visible phenotype, suppressible | partially by swmNIG.10084R/Scer\GAL4C-765 | |||
Phenotype Manifest In
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Enhanced by | |||
Statement Reference | |||
Suppressed by | |||
Statement Reference Scer\GAL4C-765, smo5A.Scer\UAS.T:Zzzz\FLAG has 1st posterior cell phenotype, suppressible by ptc[+]/ptcG12 Scer\GAL4C-765, smo5A.Scer\UAS.T:Zzzz\FLAG has wing phenotype, suppressible | partially by Scer\GAL4C-765/swm37Dh-1 Scer\GAL4C-765, smo5A.Scer\UAS.T:Zzzz\FLAG has wing phenotype, suppressible | partially by swmNIG.10084R/Scer\GAL4C-765 Scer\GAL4C-765, smo5A.Scer\UAS.T:Zzzz\FLAG has wing vein L3 phenotype, suppressible by ptc[+]/ptcG12 Scer\GAL4C-765, smo5A.Scer\UAS.T:Zzzz\FLAG has wing vein L4 phenotype, suppressible by ptc[+]/ptcG12 | |||
Additional Comments
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Genetic Interactions
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Statement Reference The reduction in distance between wing veins III and IV and partial fusions of these veins proximal to the anterior crossvein that is seen in flies expressing smo5A.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4C-765 are suppressed by ptcG12/+; the resulting flies have nearly normal wings. | |||
Xenogenetic Interactions
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Statement Reference | |||
Complementation & Rescue Data
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| Comments | |||
Stocks
( 1 ) | |||
| Bloomington | 23943 | ||
Notes on Origin
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| Discoverer | |||
External Crossreferences & Linkouts
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| Other Crossreferences | |||
| Linkouts | |||
Synonyms & Secondary IDs
( 1 ) | |||
| Reported As | |||
| Symbol Synonym | smo5A.Scer\UAS.T:Zzzz\FLAG | ||
| Name Synonym | |||
| Secondary FlyBase IDs | |||
References
( 6 ) | |||
| Research paper |
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| Personal communication to FlyBase |
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Recent Updates
External Crossreferences & Linkouts