FlyBase Allele Report: Dmel\smo[5A.UAS.Tag:FLAG]

General Information

Symbol

Dmel\smo^{5A.UAS.Tag:FLAG}

Species

D. melanogaster

Name

FlyBase ID

FBal0177836

Feature type

allele

Associated gene

Dmel\smo

Associated Insertion(s)

Carried in Construct

P{UAS-smo.5A}

Also Known As

UAS-Smo5A, UAS-smo^DN, UAS-smo^5A

Key Links

Transgenic product class

missense_variant

(Collins and Cohen, 2005)

polypeptide_post_translational_processing_variant

(Collins and Cohen, 2005)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Collins and Cohen, 2005)

polypeptide_post_translational_processing_variant

(Collins and Cohen, 2005)

Mutagen

in vitro construct

(Collins and Cohen, 2005)

Progenitor genotype

Carried in construct

P{UAS-smo.5A}

Cytology

Description

UASt regulatory sequences drive expression of a mutated form of smo in which the five putative PKA phosphorylation sites in the C-terminal, cytoplasmic tail have been mutated (amino acid replacements S667A, S687A, S740A, T755A and T785A). The smo protein is tagged with Tag:FLAG at the C-terminal end.

(Collins and Cohen, 2005)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

smo

Tagged with

Tag:FLAG

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile, with Scer\GAL4^C-765

(Collins and Cohen, 2005)

viable, with Scer\GAL4^C-765

(Collins and Cohen, 2005)

visible, with Scer\GAL4^C-765

(Casso et al., 2008, Collins and Cohen, 2005)

visible, with Scer\GAL4^C-765, smo³

(Collins and Cohen, 2005)

visible | adult stage, with Scer\GAL4^C-765

(Shalaby et al., 2017)

Phenotype Manifest In

first posterior wing cell, with Scer\GAL4^C-765

(Collins and Cohen, 2005)

first posterior wing cell, with Scer\GAL4^C-765, smo³

(Collins and Cohen, 2005)

wing, with Scer\GAL4^C-765

(Casso et al., 2008)

wing vein, with Scer\GAL4^C-765

(Shalaby et al., 2017)

wing vein L3, with Scer\GAL4^C-765

(Collins and Cohen, 2005)

wing vein L3, with Scer\GAL4^C-765, smo³

(Collins and Cohen, 2005)

wing vein L4, with Scer\GAL4^C-765

(Collins and Cohen, 2005)

wing vein L4, with Scer\GAL4^C-765, smo³

(Collins and Cohen, 2005)

Detailed Description

Statement

Reference

Expression of smo^{5A.Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^C-765 results in disrupted wing veins.

(Shalaby et al., 2017)

Expression of smo^{5A.Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^C-765 results in a reduction in the distance between veins III and IV in the wing and a partial fusions of these veins proximal to the anterior crossvein. The reduction in distance between wing veins III and IV and partial fusions of these veins proximal to the anterior crossvein that is seen in flies expressing smo^{5A.Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^C-765 are strongly enhanced by smo³/+.

(Collins and Cohen, 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, enhanceable by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, enhanceable by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)A³⁶³

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)G¹⁴⁴⁰

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)M²⁴⁴³

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by M(smoDN)K⁸⁶²

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by eIF1A⁶⁴⁵

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by eRF1⁷⁰⁹

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by jaft⁴⁴⁷

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by Trs20¹¹⁵⁹

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by mirr¹⁴⁸⁶

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by pav²⁰⁴⁶

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by pav⁸³¹

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by pav^B200

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)B-right⁹⁴²

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)E⁹⁹⁵

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)871⁸⁷¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)918⁹¹⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)986⁹⁸⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)A¹⁵⁸¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)A⁷⁷⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by Trs20⁴²¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)B-right⁴²¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)E²⁰⁸⁷

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)G²⁰⁵⁰

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)G²²⁹¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)M²⁵¹⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)N¹⁵⁰⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)N¹⁶⁴⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)O¹⁹¹⁷

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)O²⁴⁶⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by eIF1A²²³²

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by eRF1²⁶⁰⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by eRF1²⁶³³

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by jaft²⁰⁷⁵

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by jaft⁴⁷⁷

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by jaft⁷⁸⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by mirr¹⁸²⁵

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by ptc¹²³²

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)111¹¹¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1124¹¹²⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1131¹¹³¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1171¹¹⁷¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1333¹³³³

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1338¹³³⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1411¹⁴¹¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1414¹⁴¹⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1419¹⁴¹⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1422¹⁴²²

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1438¹⁴³⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1485¹⁴⁸⁵

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1496¹⁴⁹⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1551¹⁵⁵¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1575¹⁵⁷⁵

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1644¹⁶⁴⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1700¹⁷⁰⁰

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1736¹⁷³⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1823¹⁸²³

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1824¹⁸²⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1835¹⁸³⁵

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1857¹⁸⁵⁷

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1875¹⁸⁷⁵

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)1889¹⁸⁸⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)198¹⁹⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2016²⁰¹⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2038²⁰³⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)203²⁰³

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2042²⁰⁴²

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2047²⁰⁴⁷

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2070²⁰⁷⁰

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2101²¹⁰¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2117²¹¹⁷

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2135²¹³⁵

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2162²¹⁶²

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2169²¹⁶⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)219²¹⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2243²²⁴³

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2281²²⁸¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2364²³⁶⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2515²⁵¹⁵

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2546²⁵⁴⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2576²⁵⁷⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2577²⁵⁷⁷

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2578²⁵⁷⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2583²⁵⁸³

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2590²⁵⁹⁰

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2619²⁶¹⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)2640²⁶⁴⁰

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)390³⁹⁰

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)391³⁹¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)418⁴¹⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)461⁴⁶¹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)474⁴⁷⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)529⁵²⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)548⁵⁴⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)786⁷⁸⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)830⁸³⁰

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, enhanceable by E(smoDN)845⁸⁴⁵

(Collins, 2005.7.7)

NOT Enhanced by

Statement

Reference

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by Utx[+]/Utx^Δ

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by NO66[+]/NO66^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-enhanceable by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Suppressed by

Statement

Reference

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, suppressible | partially by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible | partially by Scer\GAL4^C-765/swm^37Dh-1

(Casso et al., 2008)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible | partially by swm^NIG.10084R/Scer\GAL4^C-765

(Casso et al., 2008)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by pav⁹⁶³

(Collins, 2005.7.7, Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by ptc[+]/ptc^G12

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by M(smoDN)K²⁵¹⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by S(smoDN)1378¹³⁷⁸

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by S(smoDN)1657¹⁶⁵⁷

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by S(smoDN)166¹⁶⁶

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by S(smoDN)189¹⁸⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by S(smoDN)194¹⁹⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by S(smoDN)204²⁰⁴

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by S(smoDN)2472²⁴⁷²

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by S(smoDN)2629²⁶²⁹

(Collins, 2005.7.7)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible phenotype, suppressible by S(smoDN)395³⁹⁵

(Collins, 2005.7.7)

NOT suppressed by

Statement

Reference

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by Utx[+]/Utx^Δ

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by NO66[+]/NO66^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has visible | adult stage phenotype, non-suppressible by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Suppressor of

Statement

Reference

smo^{5A.UAS.Tag:FLAG}/Scer\GAL4^ppk.1.9 is a suppressor | partially of abnormal pain response | early third instar larval stage | heat sensitive phenotype of Scer\GAL4^ppk.1.9, TkR99D^UAS.EGFP

(Im et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, enhanceable by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, enhanceable by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by E(smoDN)A³⁶³

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by E(smoDN)E⁹⁹⁵

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by E(smoDN)G¹⁴⁴⁰

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by E(smoDN)M²⁴⁴³

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by M(smoDN)K⁸⁶²

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by eIF1A⁶⁴⁵

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by eRF1⁷⁰⁹

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by jaft⁴⁴⁷

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by mirr¹⁴⁸⁶

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by pav²⁰⁴⁶

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by pav⁸³¹

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by Trs20¹¹⁵⁹

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by pav^B200

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, enhanceable by E(smoDN)B-right⁹⁴²

(Collins and Cohen, 2005)

NOT Enhanced by

Statement

Reference

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by Utx[+]/Utx^Δ

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by NO66[+]/NO66^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-enhanceable by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Suppressed by

Statement

Reference

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, suppressible | partially by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, suppressible | partially by Scer\GAL4^C-765/swm^37Dh-1

(Casso et al., 2008)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, suppressible | partially by swm^NIG.10084R/Scer\GAL4^C-765

(Casso et al., 2008)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has first posterior wing cell phenotype, suppressible by ptc[+]/ptc^G12

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein L3 phenotype, suppressible by ptc[+]/ptc^G12

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein L4 phenotype, suppressible by ptc[+]/ptc^G12

(Collins and Cohen, 2005)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing phenotype, suppressible by pav⁹⁶³

(Collins and Cohen, 2005)

NOT suppressed by

Statement

Reference

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by Utx[+]/Utx^Δ

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by NO66[+]/NO66^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^C-765, smo^{5A.UAS.Tag:FLAG} has wing vein phenotype, non-suppressible by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The disrupted wing vein phenotype characteristic for flies expressing smo^{5A.Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^C-765 is further exacerbated by combination with a single copy of any of Kdm4A^KO or Kdm4B^KO, ameliorated by combination with JHDM2^KO and not significantly modified by heterozygosity of any of the following: Kdm2^KO, Utx^Δ, lid¹⁰⁴²⁴, Jarid2^KO, NO66^KO, JMJD5^KO, JMJD7^KO, Df(3R)HSPBAP1-KO or JMJD4^KO. Combination with PSR^FM1 shows a tendency towards worsening the phenotype but the effect is not statistically significant.

(Shalaby et al., 2017)

Co-expression of smo^{5A.Scer\UAS.T:Zzzz\FLAG} significantly suppresses the withdrawal responses to a 38[o]C probe (without pre-exposure to UV) seen in early third instar larvae with TkR99D^{Scer\UAS.T:Avic\GFP-EGFP} over-expressed by Scer\GAL4^ppk.1.9.

(Im et al., 2015)

The reduction in distance between wing veins III and IV and partial fusions of these veins proximal to the anterior crossvein that is seen in flies expressing smo^{5A.Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^C-765 are suppressed by ptc^G12/+; the resulting flies have nearly normal wings.

(Collins and Cohen, 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

23943

w^*; P{UAS-smo.5A}2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Smo^5A

(Shalaby et al., 2017)

smo^{5A.Scer\UAS.T:Zzzz\FLAG}

smo^{5A.UAS.Tag:FLAG}

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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