FB2025_01 , released February 20, 2025
Allele: Dmel\14-3-3ζI.UAS
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General Information
Symbol
Dmel\14-3-3ζI.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0218565
Feature type
allele
Associated gene
Dmel\14-3-3ζ
Associated Insertion(s)
Carried in Construct
P{UAS-leo.I}
Also Known As
UASleoI
Key Links
Transgenic product class
wild_type
(Acevedo et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Acevedo et al., 2007)
Mutagen
in vitro construct
(Acevedo et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-leo.I}
Cytology
Description

UASt regulatory sequences drive expression of the 14-3-3ζ I isoform.

(Acevedo et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
14-3-3ζ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of 14-3-3ζI.Scer\UAS under the control of either Scer\GAL4αTub84B.PL, Scer\GAL4Act5C.PI or Scer\GAL4nos.UTR.T:Hsim\VP16 does not rescue the reduction in the number of pole cells per gonad seen in 14-3-3εex4 embryos.

      (Tsigkari et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      14-3-3ζI.UAS/Scer\GAL4elav.PLu rescues 14-3-3ζP2335/14-3-3ζP1188

      (Messaritou et al., 2009)

      14-3-3ζI.UAS/Scer\GAL4elav.PLu rescues 14-3-3ζP1188

      (Messaritou et al., 2009)
      Comments

      Expression of 14-3-3ζI.Scer\UAS under the control of Scer\GAL4elav.PLu partially rescues the lethality found in 14-3-3ζP1188 homozygotes and 14-3-3ζP1188/14-3-3ζP2335 heterozygotes to approximately 20% of expected.

      (Messaritou et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      14-3-3ζI.Scer\UAS
      14-3-3ζI.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (3)