FlyBase Aberration Report: Dmel\Df(2R)H3C1

General Information

Symbol

Df(2R)H3C1

Species

D. melanogaster

Name

FlyBase ID

FBab0024375

Feature type

chromosomal_deletion

Computed Breakpoints include

43F;44D3-44D8

Features within 43F--44D8

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

ptc^H3

(Matthews, 1996.2.2, Zhang et al., 1996)

Mutagen

X ray

(Matthews, 1996.2.2, Zhang et al., 1996)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Rao et al., 2001, Matthews, 1996.2.2, Zhang et al., 1996)

Breakpoints

43F;44D

(Matthews, 1996.2.2, Zhang et al., 1996)

43F;44D3-44D8

(Rao et al., 2001)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

bk1 << ptc << bk2 << wun

Genetic mapping information

Comments

Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0086252) Left limit of break 2 from inclusion of ptc (FBrf0089219) Right limit of break 2 from polytene analysis (FBrf0086252)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

ifm(2)RS4

(Babu and Ramachandra, 2007)

ptc

(Spradling et al., 1999, Zhang et al., 1996, BDGP Project Members, 1994-1999)

stmA

(Huang et al., 2004, Kumar et al., 2001)

Vps25

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

zih

(Luschnig et al., 2004)

Partially deleted / disrupted

stmA

(Rao et al., 2001)

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Acsl

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Ak2

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

CSN4

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Cul1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

CycE

(Prokopenko et al., 2000)

kermit

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)k03110

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)k07521

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)s1878

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

pnut

(BDGP Project Members, 1994-1999)

rnh1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Rs1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

RyR

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Vps28

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

wun

(Zhang et al., 1996)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

It is likely that Df(2R)H3C1 does not eliminate stmA completely.

(Rao et al., 2001)

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

The Df(2R)H3C1 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(2R)H3C1 results in 1.9% X chromosome nondisjunction and 0.8% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Fails to complement Df(2R)44CE for lethality and show the ptc phenotype but germ cell migration is normal.

(Zhang et al., 1996)

Stocks (3)

198

108896

103337

w¹¹⁸ ; Df(2R)H3C1 / CyO

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

198

(Huang et al., 2004)

Df H3C1

(Garver et al., 2006)

Df(2R)H3C1

(Tan et al., 2020, Clough et al., 2014, Szuplewski et al., 2012, Casso et al., 2008, O'Farrell et al., 2008, Babu and Ramachandra, 2007, Huang et al., 2004)

Name Synonyms

Secondary FlyBase IDs

References (25)

Report Sections

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