FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Brd3
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General Information
Symbol
Dmel\Brd3
Species
D. melanogaster
Name
FlyBase ID
FBal0001272
Feature type
allele
Associated gene
Dmel\Brd
Associated Insertion(s)
P{}Brd3
Carried in Construct
Key Links
Allele class

hypermorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypermorphic allele - genetic evidence

(Leviten and Posakony, 1996)
Mutagen
P-element activity
(Leviten and Posakony, 1996)
gamma ray
Progenitor genotype
Brd1
(Leviten and Posakony, 1996)
Associated Insertion(s)
P{}Brd3
Caused by aberration
In(3L)Brd3
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Microchaetae and macrochaetae multiplication, ectopic bristles are complete sensory organs. Ocellar, postvertical and anterior dorsocentral bristle loss due to defects in the cell fate specification in the bristle lineage.

      (Leviten and Posakony, 1996)

      Brd3 and other alleles produce more severe microchaete phenotypes, in both disc and histoblast derived tissues, as well as exhibiting the Brd1 phenotypes. This bristle loss occurs in other Brd genotypes and is most severe for Brd3 homozygotes.

      (Lindsley and Zimm, 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Brd3 has phenotype, enhanceable by DeltaCS20

      (Leviten and Posakony, 1996)

      Brd3 has phenotype, enhanceable by N55e11

      (Leviten and Posakony, 1996)

      Brd3 has phenotype, enhanceable by neur11

      (Leviten and Posakony, 1996)

      Brd3 has phenotype, enhanceable by neur1

      (Leviten and Posakony, 1996)

      Brd3 has phenotype, enhanceable by neurA101

      (Leviten and Posakony, 1996)

      Brd3 has phenotype, enhanceable by neurIP-1

      (Leviten and Posakony, 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Leviten. Posakony.

      Revertant.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Brd3
      Name Synonyms
      Secondary FlyBase IDs
        References (3)