FlyBase Allele Report: Dmel\g[50e]

General Information

Symbol

Dmel\g^50e

Species

D. melanogaster

Name

FlyBase ID

FBal0004980

Feature type

allele

Associated gene

Dmel\g

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

No alteration in detected by Southern analysis.

(Lloyd et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | male

(Lloyd et al., 2002)

abnormal eye color

(Lloyd et al., 2002, Lloyd et al., 1999)

visible

(Ooi et al., 1997)

Phenotype Manifest In

Malpighian tubule

(Lloyd et al., 1999)

pigment cell

(Lloyd et al., 2002, Lloyd et al., 1999, Ooi et al., 1997)

testis sheath

(Lloyd et al., 1999)

Detailed Description

Statement

Reference

The glue granules in the third instar larval g^50e mutant salivary glands are similar in size to wild type.

(Burgess et al., 2011)

g^50e mutants have roughly one quarter of the amount of red and brown pigment in the eye compared to wild-type flies. g^50e mutant male flies show a greater degree of male-male courtship than wild-type flies.

(Lloyd et al., 2002)

Eye colour: red pigments are reduced to 24 +/- 2% of wild-type levels in females. Red pigments are reduced to 33 +/- 3% of wild-type levels, brown pigments are reduced to 19 +/- 4% of wild-type levels in males. Malpighian tubule colour: very pale-clear in females, yellow in males (wild-type colour is orange). Testis colour: very pale (wild-type colour is bright yellow).

(Lloyd et al., 1999)

Eyes exhibit pigmentation defects and reduced number of pigment granules.

(Ooi et al., 1997)

Eye colour: orange. RK1.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

g^50e has abnormal eye color phenotype, enhanceable by w^a/w^e(g)

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by w^bf/w^e(g)

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by w^ch/w^e(g)

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by w^co/w^e(g)

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by w^e/w^e(g)

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by wⁱ/w^e(g)

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by w^t/w^e(g)

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by z¹

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by z^a

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by w^e(g)

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by w^e(g)/w¹¹¹⁸

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by w¹/w^e(g)

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, enhanceable by w^Bwx/w^e(g)

(Lloyd et al., 2002)

NOT Enhanced by

Statement

Reference

g^50e has abnormal eye color phenotype, non-enhanceable by w^a3

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, non-enhanceable by w^sat/w^e(g)

(Lloyd et al., 2002)

Suppressed by

Statement

Reference

g^50e has abnormal courtship behavior | male phenotype, suppressible by w¹¹¹⁸

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, suppressible by w^+mC

(Lloyd et al., 2002)

g^50e has abnormal eye color phenotype, suppressible by w^HSBJ

(Lloyd et al., 2002)

NOT Enhancer of

Statement

Reference

g^50e is a non-enhancer of abnormal eye color phenotype of w^a3

(Lloyd et al., 2002)

Phenotype Manifest In

Enhanced by

Statement

Reference

g^50e has pigment cell phenotype, enhanceable by w^a/w^e(g)

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by w^bf/w^e(g)

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by w^ch/w^e(g)

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by w^co/w^e(g)

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by w^e/w^e(g)

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by wⁱ/w^e(g)

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by w^t/w^e(g)

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by z¹

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by z^a

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by w^e(g)/w^e(g)

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by w^e(g)/w¹¹¹⁸

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by w¹/w^e(g)

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, enhanceable by w^Bwx/w^e(g)

(Lloyd et al., 2002)

NOT Enhanced by

Statement

Reference

g^50e has pigment cell phenotype, non-enhanceable by w^a3

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, non-enhanceable by w^sat/w^e(g)

(Lloyd et al., 2002)

Suppressed by

Statement

Reference

g^50e has pigment cell phenotype, suppressible by w^+mC

(Lloyd et al., 2002)

g^50e has pigment cell phenotype, suppressible by w^HSBJ

(Lloyd et al., 2002)

NOT Enhancer of

Statement

Reference

g^50e is a non-enhancer of pigment cell phenotype of w^a3

(Lloyd et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

w^e(g), g^50e double mutant flies have at least a 50% reduction of brown (ommochrome) and red (pteridine) pigments deposited in the eye compared to g^50e single mutants. All of the following w alleles when heterozygous with w^e(g) enhance the eye colour defective phenotype of g^50e mutants, leading to a greater reduction of red pigment within the eye: w¹¹¹⁸, w¹, w^a, w^bf, w^Bwx, w^co, w^ch, w^e, wⁱ, and w^t. In contrast, w^sat/w^e(g), g^50e mutants have similar levels of red pigment in the eye to single g^50e mutants. One copy of the w^HSBJ transgene increases the amount of red pigment in both male and female w⁺, g^50e flies. One copy of the w^+mC transgene is also sufficient to increase the amount of red pigment in the eyes of both male and female w⁺, g^50e flies. w^a3, g^50e/Y double mutant flies have similar levels of red pigment in the eye to g^50e single mutants. g^50e, z^a double mutants have a reduced amount of red pigment in the eye comparted to g^50e single mutants in both male and female flies. Likewise, g^50e, z¹ double mutant flies show decreased red eye pigment than g^50e mutants, although this reduction is greater in female flies than in male flies. w¹¹¹⁸, g^50e double mutant flies do not show the increased male-male courtship behaviour that single g^50e mutants exhibit.

(Lloyd et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

101116

g^50e

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

g^50e

(Burgess et al., 2011)

Name Synonyms

garnet50e

(Burgess et al., 2011)

Secondary FlyBase IDs

References (7)

Report Sections

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