FlyBase Allele Report: Dmel\sesB[9Ed-4]

General Information

Symbol

Dmel\sesB^9Ed-4

Species

D. melanogaster

Name

FlyBase ID

FBal0007353

Feature type

allele

Associated gene

Dmel\sesB

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Zhang et al., 1999, Nash and Janca, 1983)

Mutagen

ethyl methanesulfonate

(Janca et al., 1986)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior | recessive

(Zhang et al., 1999)

decreased rate of movement

(Zhang et al., 1999)

lethal | recessive

(Janca et al., 1986)

partially lethal | male

(Zhang et al., 1999)

partially lethal - majority die | recessive

(Nash and Janca, 1983)

viable (with sesB^org)

(Rikhy et al., 2003)

Phenotype Manifest In

Detailed Description

Statement

Reference

sesB^9Ed-4 flies are very hypoactive. sesB^9Ed-4/Df(1)HC133 flies are extremely sensitive to shock and are paralysed for more than 100 seconds after vortexing. Hemizygous males have reduced viability.

(Zhang et al., 1999)

Haplo-specific lethal mutation. Survival rate is close to that of wild type.

(Nash and Janca, 1983)

haplo-specific

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

sesB^9Ed-6

(Janca et al., 1986)

sesB^9Ed-5

(Janca et al., 1986)

sesB^9Ed-3

(Janca et al., 1986)

sesB^9Ed-2

(Janca et al., 1986)

sesB^9Ed-1

(Janca et al., 1986)

sesB³

(Janca et al., 1986)

Rescued by

sesB^9Ed-4 is rescued by sesB^+t10.3

(Zhang et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

8863

y¹ sesB^9Ed-4 v¹ f¹/FM6

Notes on Origin

Discoverer

Comments

Haplo-specific lethal allele.

(Janca et al., 1986)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

M27

(Nash and Janca, 1983)

l(1)9Ed⁴

l(1)M27

(Janca et al., 1986)

sesB^9Ed-4

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

Open Close