FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AGO104845
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General Information
Symbol
Dmel\AGO104845
Species
D. melanogaster
Name
FlyBase ID
FBal0008072
Feature type
allele
Associated gene
Dmel\AGO1
Associated Insertion(s)
P{PZ}AGO104845
Carried in Construct
Also Known As
l(2)04845
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}AGO104845
Cytology
Description

P{PZ} insertion in intron 2 of the CT20708 transcript of AGO1, 1210bp downstream of the 5' end of the transcript.

(Misra, 2000.8.25)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      AGO104845 heterozygotes and AGO104845/AGO1k08121 transheterozygotes exhibit crystalline aggregates (of Stellate protein) in spermatocytes, which are absent in control spermatocytes.

      (Bozzetti et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      AGO104845 is a suppressor of visible phenotype of E2f1RNAi.C.UAS, Scer\GAL4I-76-D

      (Li and Lu, 2009)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      AGO104845 has spermatocyte | spermatogenesis phenotype, suppressible by aubsting-1/aub[+]

      (Bozzetti et al., 2015)
      Suppressor of
      Statement
      Reference

      AGO104845 is a suppressor of eye phenotype of E2f1RNAi.C.UAS, Scer\GAL4I-76-D

      (Li and Lu, 2009)

      AGO104845 is a suppressor of antenna phenotype of E2f1RNAi.C.UAS, Scer\GAL4I-76-D

      (Li and Lu, 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The crystalline aggregates (of Stellate protein) observed in the spermatocytes of AGO104845 heterozygotes are suppressed by aubsting-1 heterozygosity.

      (Bozzetti et al., 2015)

      AGO104845 suppresses the eye and antenna traits of flies expressing E2fdsRNA.C.Scer\UAS under the control of Scer\GAL4I-76-D.

      (Li and Lu, 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Separable from: other insertions of P{PZ}. The "l(2)04845" line has multiple insertions of the P{PZ} element.

      (Kataoka et al., 2001)
      Comments
      Comments

      Not allelic to shot.

      (Gregory and Brown, 1998)

      Complements: l(2)0310503105. Complements: mam04615. Complements: mam08940. Complements: shotk04204. Complements: shotk05803. Complements: shotk10821. Complements: mamrH755.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      AGO104845
      (Lee et al., 2018, Bozzetti et al., 2015)
      l(2)04845
      (Kataoka et al., 2001, Misra, 2000.8.25, Spradling et al., 1999)
      l(2)0484504845
      (BDGP Project Members, 1994-1999)
      l(2)4845
      (Gregory and Brown, 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (10)