FB2026_02 , released June 18, 2026
Allele: Dmel\RpL3845-72
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General Information
Symbol
Dmel\RpL3845-72
Species
D. melanogaster
Name
FlyBase ID
FBal0009006
Feature type
allele
Associated gene
Dmel\RpL38
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)41Af1, EMS45-72
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Rollins et al., 1999)
Mutagen
ethyl methanesulfonate
(Lyttle, 1989, Hilliker, 1976)
Progenitor genotype
Cytology
Description

Point mutation in splice acceptor site.

(Marygold et al., 2005)

Point mutation.

(Hilliker, 1976)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:4,516,321..4,516,321 [-]
Nucleotide change:

A4516321T

Comment:

Point mutation in the splice acceptor site immediately before the initiating ATG.

(Marygold et al., 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous adults eclose with a delay of about a day compared to control flies. RpL3845-72/RpL38NC21 animals show 5% viability. These animals also show notches on the wing margin.

      (Marygold et al., 2005)

      No Minute phenotype.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Chie5.5, RpL38[+]/RpL3845-72 has visible | dominant phenotype

      (Rollins et al., 1999)

      RpL38[+]/RpL3845-72, mamg2.1 has visible | dominant phenotype

      (Rollins et al., 1999)

      RpL3845-72, ct2s has visible | dominant phenotype

      (Rollins et al., 1999)

      RpL38[+]/RpL3845-72, vg1 has visible | dominant phenotype

      (Rollins et al., 1999)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      RpL3845-72 is an enhancer of phenotype of mamg2.1

      (Rollins et al., 1999)

      RpL3845-72 is an enhancer of phenotype of vg1

      (Rollins et al., 1999)

      RpL3845-72 is an enhancer of wing phenotype of ct53d

      (Rollins et al., 1999)

      RpL3845-72 is an enhancer of wing phenotype of Nnd-1

      (Rollins et al., 1999)

      RpL3845-72 is an enhancer of phenotype of Chie5.5

      (Rollins et al., 1999)
      NOT Enhancer of
      Statement
      Reference

      RpL3845-72 is a non-enhancer of phenotype of wgl-17

      (Rollins et al., 1999)

      RpL3845-72 is a non-enhancer of phenotype of ap56f

      (Rollins et al., 1999)

      RpL3845-72 is a non-enhancer of wing phenotype of ctL32, su(Hw)e2

      (Rollins et al., 1999)
      Suppressor of
      Statement
      Reference

      RpL3845-72 is a suppressor of wing vein phenotype of NAx-E2

      (Rollins et al., 1999)

      RpL3845-72 is a suppressor of eye phenotype of Nspl-1

      (Rollins et al., 1999)
      Other
      Statement
      Reference

      Chie5.5, RpL38[+]/RpL3845-72 has wing phenotype

      (Rollins et al., 1999)

      RpL3845-72, vg[+]/vg1 has wing phenotype

      (Rollins et al., 1999)

      RpL3845-72, mamg2.1/mam[+] has wing phenotype

      (Rollins et al., 1999)

      Chi[+]/Chie5.5, RpL3845-72 has wing phenotype

      (Rollins et al., 1999)

      RpL3845-72, ct2s has wing phenotype

      (Rollins et al., 1999)

      RpL38[+]/RpL3845-72, vg1 has wing phenotype

      (Rollins et al., 1999)

      RpL38[+]/RpL3845-72, mamg2.1 has wing phenotype

      (Rollins et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Hilliker.

      (Lyttle, 1989, Hilliker, 1976)

      Separable from: a Pin mutation.

      (Rollins et al., 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      EMS45-72
      (Duffy et al., 1996, Hilliker, 1976)
      RpL381
      (Marygold et al., 2005)
      RpL3845-72
      (Gambetta and Müller, 2009.8.18)
      l(2)41Af1
      (Marygold et al., 2005, Lyttle, 1989)
      l(2)41Af45-72
      (Rollins et al., 1999)
      l(2)EMS45-72
      (Eberl et al., 1993)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)