FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\kst01318
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General Information
Symbol
Dmel\kst01318
Species
D. melanogaster
Name
FlyBase ID
FBal0009407
Feature type
allele
Associated gene
Dmel\kst
Associated Insertion(s)
P{PZ}kst01318
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}kst01318
Cytology
Description

Insertion of a P{PZ} element within the 5' untranslated region, between positions 662 and 663 of intron 1.

(Thomas et al., 1998)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Border cells migrate ahead of outer follicle cells in 72% of kst2/kst01318 egg chambers.

      (Urwyler et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      kst[+]/kst01318 is an enhancer of lethal | embryonic stage | recessive | partially phenotype of peb308

      (Wilk et al., 2004)
      Suppressor of
      Statement
      Reference

      kst[+]/kst01318 is a suppressor of visible | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      Other
      Statement
      Reference

      kst[+]/kst01318, vri5R7.2 has visible phenotype

      (Szuplewski et al., 2003)

      kst01318, vri5R7.2/vri[+] has visible | dominant phenotype

      (Szuplewski et al., 2003)
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      kst01318/kst2 has follicle cell phenotype, non-enhanceable by sosief00514/CG13636[+]

      (Urwyler et al., 2012)
      NOT suppressed by
      Statement
      Reference

      kst01318/kst2 has follicle cell phenotype, non-suppressible by sosief00514/CG13636[+]

      (Urwyler et al., 2012)
      Suppressor of
      Statement
      Reference

      kst[+]/kst01318 is a suppressor of eye | heat sensitive phenotype of peb1

      (Wilk et al., 2004)

      kst01318 is a suppressor of phenotype of BicDr

      (Nguyen, 1997.4.17, Nguyen and Suter, 1997)

      kst01318 is a suppressor of phenotype of BicDR26

      (Nguyen and Suter, 1997)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      sosief00514/+ does not increase the penetrance of the follicle cell migration coordination defect (border cells migrating ahead of outer follicle cells) seen in kst2/kst01318 egg chambers.

      (Urwyler et al., 2012)

      S48-5/kst01318 mutants show 5.62%+-1.13 misrotated ommatidia compared to 9.55%+-1.43 seen in S48-5 mutants alone.

      (Gaengel and Mlodzik, 2003)

      vri5R7.2 kst01318 double heterozygotes have missing hairs at the anterior margin and notching at the posterior margin of the wing.

      (Szuplewski et al., 2003)

      kst01318 is a strong dominant suppressor of BicDr.

      (Nguyen, 1997.4.17)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Induced with: l(3)72Dq01318.

      (Thomas and MacIver, 1999.8.19)
      Comments
      Comments

      This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

      Revertants fully complement kst1, kst2 and Df(3L)1226.

      (Thomas et al., 1998)

      Complements: l(3)0914309143. Complements: l(3)neo91.

      (BDGP Project Members, 1994-1999)

      The lethality of the kst01318 chromosome is not associated with a closely linked P{PZ} insertion.

      (Nguyen, 1997.4.17)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      kst-01318
      (Gaengel and Mlodzik, 2003)
      kst01318
      kstP1528
      (Urwyler et al., 2012)
      l(3)01318
      (Thomas et al., 1998)
      l(3)0131801318
      Name Synonyms
      Secondary FlyBase IDs
        References (12)