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General Information
Symbol
Dmel\Doa01705b
Species
D. melanogaster
Name
FlyBase ID
FBal0009424
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(3)01705
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The P{PZ} element is inserted 131 nucleotides 5' to the first non-coding exon of the 105kDa Doa coding transcript and 1667 nucleotides 5' to its initiating AUG.

Insertion components
P{PZ}Doa01705b
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In DoaDem/Doa01705b mutant flies, the leg segments distal to the first tarsus often fail to elongate. The femur and claws form normally. Defects are seen in both the mesothoracic and metathoracic tarsi.

In DoaSu(Mrt9)/Doa01705b mutants where the DoaSu(Mrt9) allele is from the mother more females are observed than males. The flies have rough eyes, loss of head, scutellar or postalar bristles, fragile wings with small black spots and/or ectopic wing veins and disorganisation of the vaginal bristles. The flies have very rough eyes, some misoriented head bristles and disorganisation of the vaginal bristles. When the Doa01705b allele comes from the mother there are no survivors.

Transheterozygotes with Doa7, In(3)Msu1, In(3)Msu2 or DoaDem have rough eyes and duplicated scutellar bristles.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference

Doa01705b is a suppressor of phenotype of wa

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

A. Spradling.

Separable from: P{PZ}01705a. Evidence suggests that the "l(3)01705" line contains 2 P{PZ} insertions; one at 39B (P{PZ}01705a) corresponding to the site of the STS sequence from this line (G00743), and one at 98F (P{PZ}Doa01705b) which causes a mutation in Doa.

Comments
Comments

Fails to complement the recessive lethality of some, but not all, alleles of Doa.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Doa01705
l(3)0170501705
Name Synonyms
Secondary FlyBase IDs
    References (8)