The nerve-evoked excitatory junctional potential (EJP) amplitudes in mutant larvae are reduced to about half that of controls. EJP amplitudes are not reduced by a fatigue of evoked release, because responses sequentially recorded at 0.2 Hz do not progressively diminish. The quantal content of evoked release in homozygotes is reduced to a third to a half of control.
Shows no interaction with N pathway mutants.
Third instar larvae contain circulating melanotic capsules, and die as early pupae.
The Bolwig's organs show variable disruption of cell clustering in homozygous embryos. A number of photoreceptors are displaced along the path of the Bolwig's nerve (BN) in some embryos. The BN defasciculates on the surface of the optic lobe anlagen in most embryos. the defasciculated BN usually projects abnormally and forms loop-like structures.
Germline clones produce eggs with patterning defects: anterior head defects and variable abdominal segmentation defects. Lethality occurs during the larval and pupal stages.
visible rough eyes, bent wings, thin, short bristles