FlyBase Allele Report: Dmel\sc[8]

General Information

Symbol

Dmel\sc⁸

Species

D. melanogaster

Name

FlyBase ID

FBal0015197

Feature type

allele

Associated gene

Dmel\sc

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Lindsley and Zimm, 1992)

Progenitor genotype

Caused by aberration

In(1)sc⁸

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die

(Hess, 1963, Hess, 1962)

viable

(Golovnin et al., 2003)

visible

(Golovnin et al., 2003)

visible | recessive

(Gomez-Skarmeta et al., 1995)

Phenotype Manifest In

anepisternum

(Lindsley and Zimm, 1992)

anterior notopleural bristle

(Gomez-Skarmeta et al., 1995)

macrochaeta

(Lindsley and Zimm, 1992)

scutellar bristle

(Golovnin et al., 2003)

sternopleural bristle

(Lindsley and Zimm, 1992)

supraalar bristle

(Lindsley and Zimm, 1992)

Detailed Description

Statement

Reference

Mutants show loss of the scutellar bristle.

(Golovnin et al., 2003)

Anterior notopleural macrochaetae are removed.

(Gomez-Skarmeta et al., 1995)

Slight sc; supra-alars, sternopleurals, or other bristles sometimes affected. Extra bristles may be present. Shows ac^Hw-1 effect and may be recognized in heterozygote, homozygote, or male by presence of one or more hairs on anterior mesopleural region. RK2A.

(Lindsley and Zimm, 1992)

sc⁸/0 male nearly lethal; survivors show variegation for y and ac; lethality suppressed by a Y chromosome, partially suppressed by parts of the Y.

(Hess, 1963, Hess, 1962)

The ac^Hw-1 effect interacts strongly with h to produce extremely hairy wings.

(Steinberg, 1942)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

sc⁸ has scutellar bristle phenotype, enhanceable by Df(3R)GC14/mod(mdg4)^ul

(Golovnin et al., 2003)

sc⁸ has scutellar bristle phenotype, enhanceable by mod(mdg4)^ul/mod(mdg4)^ul

(Golovnin et al., 2003)

sc⁸ has scutellar bristle phenotype, enhanceable by su(Hw)⁷/su(Hw)^V

(Golovnin et al., 2003)

NOT suppressed by

Statement

Reference

sc⁸ has phenotype, non-suppressible by su(Hw)²

(Lindsley and Grell, 1968)

Other

Statement

Reference

mod(mdg4)^ul, sc⁸ has humeral bristle phenotype

(Golovnin et al., 2003)

mod(mdg4)^ul, sc⁸ has presutural bristle phenotype

(Golovnin et al., 2003)

sc⁸, su(Hw)⁷/su(Hw)^V has presutural bristle phenotype

(Golovnin et al., 2003)

sc⁸, su(Hw)⁷/su(Hw)^V has anterior supraalar bristle phenotype

(Golovnin et al., 2003)

mod(mdg4)^ul, sc⁸ has anterior supraalar bristle phenotype

(Golovnin et al., 2003)

Df(3R)GC14/mod(mdg4)^ul, sc⁸ has humeral bristle phenotype

(Golovnin et al., 2003)

Df(3R)GC14/mod(mdg4)^ul, sc⁸ has presutural bristle phenotype

(Golovnin et al., 2003)

Df(3R)GC14/mod(mdg4)^ul, sc⁸ has anterior supraalar bristle phenotype

(Golovnin et al., 2003)

sc⁸, su(Hw)⁷/su(Hw)^V has humeral bristle phenotype

(Golovnin et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

In(1)sc⁸ ; su(Hw)^V/su(Hw)⁷ animals show loss of a number of bristles. Bristle pigmentation is normal in these animals. In(1)sc⁸ ; mod(mdg4)^ul/mod(mdg4)^ul and In(1)sc⁸ ; mod(mdg4)^ul/Df(3R)GC14 animals show loss of a number of bristles. Bristle pigmentation is normal in these animals.