Heterozygote adults show no transformation phenotype. Hemizygotes are pupal lethal, homozygotes are larval lethal. trxZ16/Df(3R)red-P52 hemizygotes show phenotypes that suggest decreased Scr function (transformation of T1 structures to a T2 identity), decreased Ubx function (transformation of T3 to T2), decreased abd-A function (transformation of A2-A7 to A1) and decreased Abd-B function (transformation of posterior abdominal segments to more anterior abdominal identities). Scr group transformations include the development of mesothoracic tibial preapical bristles or mesothoracic tibial apical bristles on the prothoracic tibia, reduced numbers of sex comb teeth (in males), development of sternopleural bristles or katepisternal bristles on the T1 segment. Ubx group transformations include haltere to wing, metathoracic laterotergite to scutum, the development of T3 sternopleural bristles, mesothoracic tibial preapical bristles or mesothoracic tibial apical bristles on the metathoracic tibia. abd-A group transformations include the development of A1 type bristles on abdominal tergites 2 to 3. Abd-B group transformations include the pigmentation of abdominal tergites 5 to 6 in males, and enlargement of abdominal tergite 7. trxE3/trxZ16 flies frequently have missing dorsal head structures, including different combinations of ocelli, ocellar bristles, and postvertical bristles. The posterior border of the A1 tergite may have Uab-like bristles and dark pigmentation. They can also exhibit incomplete dorsal fusion of tergites. The dorsal anal plate of females may be incomplete. trxJY21/trxZ16 flies show mesosternal bristles on T3 and T1, partial transformation of haltere to wing, transformation of dorsal T3 to mesonotum typical of T2, sternopleural bristles in T1 and T3, development of a preapical bristle on T3 and often have abnormal abdominal spiracles and abnormal sternites. Males occasionally develop T2 legs from their genital discs.