FlyBase Allele Report: Dmel\px[k08316]

General Information

Symbol

Dmel\px^k08316

Species

D. melanogaster

Name

FlyBase ID

FBal0064327

Feature type

allele

Associated gene

Dmel\px

Associated Insertion(s)

P{lacW}px^k08316

Carried in Construct

Also Known As

l(2)k08316

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}px^k08316

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:22,514,131..22,514,131 [+]

(Levis, 2001.2.19, Spradling, 1999.12.9, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates autosomal dominant cerebellar ataxia

modeled by Hsap\ATXN8OS^CTG112.UAS

(Mutsuddi et al., 2004)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

px[+]/px^k08316 is an enhancer of visible | dominant phenotype of Egfr^E1

(Read et al., 2005)

px[+]/px^k08316 is an enhancer of abnormal neuroanatomy phenotype of Hsap\ATXN8OS^CTG112.UAS, Scer\GAL4^GMR.PF

(Mutsuddi et al., 2004)

NOT Enhancer of

Statement

Reference

px[+]/px^k08316 is a non-enhancer of visible phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

Suppressor of

Statement

Reference

px[+]/px^k08316 is a suppressor of visible phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

px[+]/px^k08316 is a suppressor of visible phenotype of Ret^GMR.PR

(Read et al., 2005)

px[+]/px^k08316 is a suppressor of visible | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

px^k08316 is a suppressor of visible phenotype of upd1^GMR.PB

(Bach et al., 2003)

NOT Suppressor of

Statement

Reference

px[+]/px^k08316 is a non-suppressor of visible phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

Phenotype Manifest In

Enhancer of

Statement

Reference

px[+]/px^k08316 is an enhancer of eye phenotype of Egfr^E1

(Read et al., 2005)

NOT Enhancer of

Statement

Reference

px[+]/px^k08316 is a non-enhancer of eye phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

Suppressor of

Statement

Reference

px[+]/px^k08316 is a suppressor of eye phenotype of Ret^MEN2B.GMR

(Read et al., 2005)

px[+]/px^k08316 is a suppressor of eye phenotype of Ret^GMR.PR

(Read et al., 2005)

px[+]/px^k08316 is a suppressor of eye | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

px^k08316 is a suppressor of eye phenotype of upd1^GMR.PB

(Bach et al., 2003)

NOT Suppressor of

Statement

Reference

px[+]/px^k08316 is a non-suppressor of eye phenotype of Ret^MEN2A.GMR

(Read et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10787

y¹ w^67c23; P{lacW}px^k08316/CyO

Kyoto

111240

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}42D P{lacW}px^k08316 /CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: mei-W68^k05603. Complements: l(2)k08307^k08307.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

l(2)k08316

(Mutsuddi et al., 2004, Li et al., 2003, Levis, 2001.2.19, Spradling, 1999.12.9, Spradling et al., 1999)

l(2)k08316^k08316

(BDGP Project Members, 1994-1999)

px^k08316

px^k08613

(Bach et al., 2003)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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