FlyBase Allele Report: Dmel\mod(mdg4)[L3101]

General Information

Symbol

Dmel\mod(mdg4)^L3101

Species

D. melanogaster

Name

FlyBase ID

FBal0087001

Feature type

allele

Associated gene

Dmel\mod(mdg4)

Associated Insertion(s)

P{lacW}mod(mdg4)^L3101

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}mod(mdg4)^L3101

Cytology

Description

Insertion of P{lacW} in the third exon at nucleotide 153,269 of AE003734.

(Mongelard et al., 2002)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:21,376,605..21,376,605 [+]

(Brumby et al., 2002, Mongelard et al., 2002, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates autosomal dominant cerebellar ataxia

modeled by Hsap\ATXN8OS^CTG112.UAS

(Mutsuddi et al., 2004)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(BDGP Project Members, 1994-1999)

lethal - all die before end of larval stage | recessive

(Mongelard et al., 2002)

some die during larval stage | recessive

(Mongelard et al., 2002)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

mod(mdg4)^L3101/mod(mdg4)[+] is a suppressor of abnormal neuroanatomy phenotype of Hsap\ATXN8OS^CTG112.UAS, Scer\GAL4^GMR.PF

(Mutsuddi et al., 2004)

NOT Suppressor of

Statement

Reference

mod(mdg4)^L3101/mod(mdg4)^ul is a non-suppressor of visible | recessive phenotype of ct⁶

(Mongelard et al., 2002)

mod(mdg4)^L3101/mod(mdg4)^ul is a non-suppressor of abnormal body color | recessive phenotype of y²

(Mongelard et al., 2002)

mod(mdg4)^L3101/mod(mdg4)^ul is a non-suppressor of visible | recessive phenotype of y²

(Mongelard et al., 2002)

Phenotype Manifest In

Suppressor of

Statement

Reference

mod(mdg4)^L3101 is a suppressor of eye phenotype of CycE^JP

(Brumby et al., 2002)

NOT Suppressor of

Statement

Reference

mod(mdg4)^L3101/mod(mdg4)^ul is a non-suppressor of wing phenotype of ct⁶

(Mongelard et al., 2002)

mod(mdg4)^L3101/mod(mdg4)^ul is a non-suppressor of adult epidermis phenotype of y²

(Mongelard et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Mutant strongly suppresses the CycE^JP rough eye phenotype.

(Brumby et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

mod(mdg4)^ul

(Mongelard et al., 2002)

mod(mdg4)^T6

(Mongelard et al., 2002)

Fails to complement

mod(mdg4)^neo129

(Mongelard et al., 2002)

mod(mdg4)⁰³⁸⁵²

(Mongelard et al., 2002)

Comments

Member of Group I complementation group. Complementation statement based on transheterozygous phenotype in terms of suppression or non-suppression of y² and ct⁶ visible phenotypes.

(Mongelard et al., 2002)

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10312

y¹ w¹¹¹⁸; P{lacW}mod(mdg4)^L3101/TM3, Ser¹

Kyoto

111048

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}82B P{lacW}mod(mdg4)^L3101/TM6B, P{Car20y}TPN1, Tb¹

Notes on Origin

Discoverer

Comments

Complements: Hsrω⁰⁵²⁴¹.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

l(3)L3101

(Mutsuddi et al., 2004, Beaton, 1999.12.12)

l(3)L3101^L3101

(BDGP Project Members, 1994-1999)

mod(mdg4)^L3101

(Lo et al., 2016)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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