FB2026_02 , released June 18, 2026
Allele: Dmel\cora10
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General Information
Symbol
Dmel\cora10
Species
D. melanogaster
Name
FlyBase ID
FBal0089382
Feature type
allele
Associated gene
Dmel\cora
Associated Insertion(s)
Carried in Construct
Also Known As
cor10
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Ward et al., 2001)
Mutagen
ethyl methanesulfonate
(Lamb et al., 1998)
Progenitor genotype
Cytology
Description

Amino acid replacement: A393S.

(Ward et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:19,237,013..19,237,013 [+]
Nucleotide change:

G19237013T

Amino acid change:

A393S | cora-PA; A393S | cora-PB; A393S | cora-PC; A393S | cora-PE; A393S | cora-PF; A393S | cora-PG

Reported amino acid change:

A393S

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Ward et al., 2001)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes die as embryos or larvae. Homozygous embryos have a faint cuticle. Adult escapers are produced.

      (Lamb et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      cora10 is a suppressor of visible | dominant phenotype of EgfrE1

      (Lamb et al., 1998)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      cora10 is a suppressor of eye phenotype of EgfrE1

      (Lamb et al., 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Slightly suppresses the rough eye phenotype of EgfrE1/+ heterozygotes.

      (Lamb et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially complements

      cora3

      (Lamb et al., 1998)

      cora2

      (Lamb et al., 1998)
      Fails to complement

      cora1

      (Lamb et al., 1998)
      Rescued by

      cora10 is rescued by cora1.Ubi-p63E

      (Lamb et al., 1998)
      Partially rescued by

      cora10 is partially rescued by cora1-383.UAS.Tag:MYC/Scer\GAL4T80

      (Ward et al., 2001)
      Comments

      cora10 animals rescued by expression of cora1-383.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4T80 are fertile.

      (Ward et al., 2001)

      cora3 almost fully complements cora10 and cora11.

      (Lamb et al., 1998)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cor10
      (Ward et al., 2001, Lamb et al., 1998, Ward et al., 1998)
      cora10
      Name Synonyms
      Secondary FlyBase IDs
        References (3)