FlyBase Allele Report: Dmel\Fs(2)Ket[RX13]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Fs(2)Ket^RX13

General Information

Symbol

Dmel\Fs(2)Ket^RX13

Species

D. melanogaster

Name

FlyBase ID

FBal0089693

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Also Known As

ketel^rX13

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

(Erdelyi et al., 1997)

Progenitor genotype

(Erdelyi et al., 1997)

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 animals die as second instar larvae. The larvae become sluggish and die within a day without any apparent morphological defect. Females containing Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 germline clones deposit normal looking eggs. The eggs are fertilised, but embryogenesis does not occur due to the lack of cleavage nuclei formation following fertilisation. Eggs derived from females containing homozygous follicle cell clones hatch at a reduced rate compared to eggs derived from control females. The frequency and size of homozygous clones in the wing and tergites is similar to control clones.

(Tirian et al., 2000)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Fs(2)Ket^RX13, Pen^D14 has increased mortality during development | maternal effect phenotype, enhanceable by Scer\GAL4^{VP16.nanos.UTR}/Pen^NLSB-.UASp

(Virágh et al., 2012)

Fs(2)Ket^RX13, Pen^D14 has increased mortality during development | maternal effect phenotype, enhanceable by Pen^SNLSB-.UASp/Scer\GAL4^{VP16.nanos.UTR}

(Virágh et al., 2012)

NOT Enhanced by

Statement

Reference

Fs(2)Ket^RX13 has increased mortality during development | maternal effect phenotype, non-enhanceable by Pen^D14

(Virágh et al., 2012)

Fs(2)Ket^RX13, Pen^D14 has increased mortality during development | maternal effect phenotype, non-enhanceable by Scer\GAL4^{VP16.nanos.UTR}/Pen^CASB-.UASp

(Virágh et al., 2012)

Fs(2)Ket^RX13, Pen^D14 has increased mortality during development | maternal effect phenotype, non-enhanceable by Scer\GAL4^{VP16.nanos.UTR}/Pen^ΔIBB.UASp

(Virágh et al., 2012)

NOT suppressed by

Statement

Reference

Fs(2)Ket^RX13, Pen^D14 has increased mortality during development | maternal effect phenotype, non-suppressible by Scer\GAL4^{VP16.nanos.UTR}/Pen^CASB-.UASp

(Virágh et al., 2012)

Fs(2)Ket^RX13, Pen^D14 has increased mortality during development | maternal effect phenotype, non-suppressible by Scer\GAL4^{VP16.nanos.UTR}/Pen^ΔIBB.UASp

(Virágh et al., 2012)

Fs(2)Ket^RX13 has increased mortality during development | maternal effect phenotype, non-suppressible by Pen^D14

(Virágh et al., 2012)

NOT Enhancer of

Statement

Reference

Fs(2)Ket^RX13 is a non-enhancer of increased mortality during development | maternal effect phenotype of Pen^D14

(Virágh et al., 2012)

NOT Suppressor of

Statement

Reference

Fs(2)Ket^RX13 is a non-suppressor of increased mortality during development | maternal effect phenotype of Pen^D14

(Virágh et al., 2012)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is rescued by Scer\GAL4^αTub84B.PL/Fs(2)Ket^UAS.cVa

(Villányi et al., 2008)

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is rescued by Scer\GAL4^elav.PLu/Fs(2)Ket^UAS.cVa

(Villányi et al., 2008)

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is rescued by Scer\GAL4^NP5130/Fs(2)Ket^UAS.cVa

(Villányi et al., 2008)

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is rescued by Scer\GAL4^vg.PB/Fs(2)Ket^UAS.cVa

(Villányi et al., 2008)

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is rescued by Fs(2)Ket^S317T.P446L

(Timinszky et al., 2002)

Not rescued by

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is not rescued by Scer\GAL4^ey.PH/Fs(2)Ket^UAS.cVa

(Villányi et al., 2008)

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is not rescued by Scer\GAL4^ptc-559.1/Fs(2)Ket^UAS.cVa

(Villányi et al., 2008)

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is not rescued by Scer\GAL4^en-e16E/Fs(2)Ket^UAS.cVa

(Villányi et al., 2008)

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is not rescued by Scer\GAL4^Dll-md23/Fs(2)Ket^UAS.cVa

(Villányi et al., 2008)

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 is not rescued by Scer\GAL4^twi.PG/Fs(2)Ket^UAS.cVa

(Villányi et al., 2008)

Comments

Fs(2)Ket^RX13/Df(2L)Fs(2)Ket-RX32 ; Fs(2)Ket^S317T.P446L zygotes are fully viable and fertile.

(Timinszky et al., 2002)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Revertant.

(Timinszky et al., 2002, Erdelyi et al., 1997)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Fs(2)Ket^RX13

imp-β^KetRX13

(Virágh et al., 2012)

ketel^rX13

(Villányi et al., 2008, Timinszky et al., 2002, Lippai et al., 2000, Tirian et al., 2000)

ketel^rx13

(Natalizio and Matera, 2013)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections