FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mbtP2
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General Information
Symbol
Dmel\mbtP2
Species
D. melanogaster
Name
FlyBase ID
FBal0093834
Feature type
allele
Associated gene
Dmel\mbt
Associated Insertion(s)
P{lacW}mbtP2
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Melzig et al., 1998)
Progenitor genotype
Associated Insertion(s)
P{lacW}mbtP2
Cytology
Description

Insertion within the first exon, 181bp downstream of the predicted translation start site.

(Melzig et al., 1998)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Prominent reduction in the mushroom body neuropile size in the hemizygous or homozygous state: Kenyon cell number is reduced. Flies also exhibit a rough eye phenotype, a variable number of photoreceptor cells are missing, and bristle malformations.

      (Melzig et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      mbtP2 is a non-enhancer of visible phenotype of RalaS25N.UAS, Scer\GAL4sca-537.4

      (Sawamoto et al., 1999)
      NOT Suppressor of
      Statement
      Reference

      mbtP2 is a non-suppressor of visible phenotype of RalaS25N.UAS, Scer\GAL4sca-537.4

      (Sawamoto et al., 1999)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      mbtP2 is rescued by mbtUAS.cMa/Scer\GAL4unspecified

      (Melzig et al., 1998)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the element reverts the mutant phenotype to wild type.

      (Melzig et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mbtP2
      Name Synonyms
      Secondary FlyBase IDs
        References (2)