FlyBase Allele Report: Dmel\dco[i3-193]

General Information

Symbol

Dmel\dco^i3-193

Species

D. melanogaster

Name

FlyBase ID

FBal0102766

Feature type

allele

Associated gene

Dmel\dco

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Zilian et al., 1999)

Progenitor genotype

P{PZ}Chchd3⁰³⁶⁷⁰

(Zilian et al., 1999)

Caused by aberration

Df(3R)dco^i3-193

Cytology

Description

Deletion extending from P{PZ} of l(3)03670⁰³⁶⁷⁰ into the 5' UTR of the dco transcription unit. The deletion fuses the first 1005bp of the 1747bp second intron of dco to the first non-coding exon of the l(3)03670 transcript.

(Zilian et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Zilian et al., 1999)

Phenotype Manifest In

adult external head

(Zilian et al., 1999)

eye

(Zilian et al., 1999)

imaginal disc

(Zilian et al., 1999)

ommatidium

(Zilian et al., 1999)

tarsal segment

(Zilian et al., 1999)

wing

(Zilian et al., 1999)

wing vein

(Zilian et al., 1999)

Detailed Description

Statement

Reference

dco³ in combination with dco^le88, dco^i3-193, dco^S053813, dco^S139602, dco^S091510 and dco^P103 : show lethality during larval or early pupal stages with typical dco³ phenotype (swollen tarsi with or without head defects). Discs overgrown. dco² in combination with dco^i3-193 or dco^S139602 : show lethality during larval or early pupal stages, with abnormal discs with granular zone and abnormal folding. dco¹⁸ in combination with dco^le88, dco^i3-193, or dco^S053813 : show lethality during larval stages. dco^le88 in combination with dco^i3-193 or dco^S053813 : show lethality during larval stages with a discless phenotype. dco^i3-193 in combination with dco^S053813 : show lethality during larval stages. dco^i3-193 in combination with dco^S091510 : show lethality during larval or early pupal stages with small discs phenotype. dco^i3-193 in combination with dco^S139602 : show lethality during larval or early pupal stages with discless phenotype. dco^i3-193 in combination with dco^S144701 : adult viable with reduced eyes, disordered facets and minor wing vein defects. dco^i3-193 in combination with dco^P103 : adult viable with narrow wings and abnormal discs with granular zone and abnormal folding.