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General Information
Symbol
Dmel\SmD3lex47
Species
D. melanogaster
Name
FlyBase ID
FBal0102832
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Deficiency removing a significant portion of the SmD3 and Oda genes.

Imprecise excision of the P{lacW} insertion causes a deletion that removes most of the transcription unit and the entire open reading frame.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Smaller number of PNS neurons express 22C10 in homozygous embryos and PNS axons dispay severe defects in growth cone guidance and fasciculation. Most noticeable phenotype is splitting of the intersegmental nerve into two fascicles, the ISN 'loop' phenotype. Defects in the CNS are similar to those observed in the PNS. Numerous muscles are missing, displaced or exhibit aberrant shapes. Embryos also contain many mononucleate myoblasts that fail to fuse into muscle syncytia. Defects also in the visceral and cardiac musculature.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
SmD3lex47
guflex47
Name Synonyms
Secondary FlyBase IDs
    References (3)