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General Information
Symbol
Dmel\trioGEF1.GMR.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0117295
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

GMR regulatory sequences drive expression of the trio GEF1 domain tagged at the 3' end with 8 copies of the Tag:MYC tag.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing trioGEF1.GMR.T:Hsap\MYC have severely disrupted eye morphology and highly aberrant photoreceptor axon projections.

Animals expressing trioGEF1.GMR.T:Hsap\MYC show defects in photoreceptor axon projections.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

trioGEF1.GMR.Tag:MYC has phenotype, enhanceable by MtlGMR.PN

trioGEF1.GMR.Tag:MYC has photoreceptor cell & axon phenotype, enhanceable by MtlGMR.PN

trioGEF1.GMR.Tag:MYC has photoreceptor cell & axon phenotype, enhanceable by Rac1GMR.PNe

NOT Enhanced by
Statement
Reference

trioGEF1.GMR.Tag:MYC has phenotype, non-enhanceable by Cdc42GMR.PN

trioGEF1.GMR.Tag:MYC has phenotype, non-enhanceable by Rho1GMR.PH

Suppressed by
Statement
Reference

trioGEF1.GMR.Tag:MYC has photoreceptor cell & axon phenotype, suppressible by Rac1J10/Rac1J10

trioGEF1.GMR.Tag:MYC has photoreceptor cell & axon phenotype, suppressible by Rac2Δ/Rac2Δ

NOT suppressed by
Statement
Reference

trioGEF1.GMR.Tag:MYC has eye phenotype, non-suppressible by MtlΔ/MtlΔ

trioGEF1.GMR.Tag:MYC has photoreceptor cell & axon phenotype, non-suppressible by MtlΔ/MtlΔ

trioGEF1.GMR.Tag:MYC has phenotype, non-suppressible by Cdc42GMR.PN

trioGEF1.GMR.Tag:MYC has phenotype, non-suppressible by Rho1GMR.PH

Additional Comments
Genetic Interactions
Statement
Reference

The photoreceptor axon projection defects caused by expression of trioGEF1.GMR.T:Hsap\MYC are enhanced by MtlGMR.PN or Rac1GMR.PNe.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
trioGEF1.GMR.T:Hsap\MYC
trioGEF1.GMR.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (2)