FlyBase Allele Report: Dmel\scrib[882]

General Information

Symbol

Dmel\scrib⁸⁸²

Species

D. melanogaster

Name

FlyBase ID

FBal0127891

Feature type

allele

Associated gene

Dmel\scrib

Associated Insertion(s)

Carried in Construct

Also Known As

l(3)882

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Zeitler et al., 2004, Wu et al., 2001)

Mutagen

ethyl methanesulfonate

(Zeitler et al., 2004, Wu et al., 2001)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | larval stage (with scrib⁶⁷³)

(Zeitler et al., 2004)

lethal - all die before end of P-stage (with scrib¹)

(Zeitler et al., 2004)

lethal - all die before end of pupal stage (with Df(3R)Tl-X)

(Zeitler et al., 2004)

lethal - all die before end of pupal stage (with scrib⁶⁷³)

(Zeitler et al., 2004)

lethal - all die before end of pupal stage (with scrib^dt6)

(Zeitler et al., 2004)

lethal - all die before end of pupal stage (with scrib^ird15)

(Zeitler et al., 2004)

some die during pharate adult stage (with scrib¹)

(Zeitler et al., 2004)

some die during pupal stage (with Df(3R)Tl-X)

(Zeitler et al., 2004)

some die during pupal stage (with scrib⁶⁷³)

(Zeitler et al., 2004)

some die during pupal stage (with scrib^dt6)

(Zeitler et al., 2004)

some die during pupal stage (with scrib^ird15)

(Zeitler et al., 2004)

viable (with scrib^dt14)

(Zeitler et al., 2004)

Phenotype Manifest In

wing disc (with scrib⁶⁷³)

(Zeitler et al., 2004)

Detailed Description

Statement

Reference

Like wild type, cells from scrib⁸⁸²/scrib⁶⁷³ transheterozygous wing discs are arranged in epithelial monolayers and maintain the folded structure of the tissue.

scrib⁸⁸²/scrib⁶⁷³ transheterozygous wing discs show a very slight increase in both the surface area and volume compared to wild type.

(Zeitler et al., 2004)

Some scrib⁸⁸²/scrib^j7B3 animals survive to adulthood.

(Wu et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

scrib^dt14

(Zeitler et al., 2004)

Fails to complement

scrib^ird15

(Zeitler et al., 2004)

scrib¹

(Zeitler et al., 2004)

scrib⁶⁷³

(Zeitler et al., 2004)

scrib^dt12

(Zeitler et al., 2004)

scrib^dt6

(Zeitler et al., 2004)

scrib^ird15

(Wu et al., 2001)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Transheterozygous combinations between scrib^dt6, scrib^dt12 and scrib⁸⁸² suggest that scrib^dt6 is the most severe mutation of these three.

(Zeitler et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

l(3)882

(Zeitler et al., 2004, Wu et al., 2001)

scrib 6

(Zeitler et al., 2004)

scrib⁸⁸²

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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