FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\drprEP522
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General Information
Symbol
Dmel\drprEP522
Species
D. melanogaster
Name
FlyBase ID
FBal0130405
Feature type
allele
Associated gene
Dmel\drpr
Associated Insertion(s)
P{EP}drprEP522
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Freeman et al., 2003)
Mutagen
P-element activity
(Freeman et al., 2003, Gene Disruption Project members, 2001-, FlyBase, 1996-)
Progenitor genotype
Associated Insertion(s)
P{EP}drprEP522
Cytology
Description

The P{EP}drprEP522 insertion maps within both drpr and Oseg4 (overlapping genes on the same strand).

(FlyBase, 1996-)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous larvae show extremely reduced motility compared to control heterozygous larvae and are profoundly uncoordinated.

      (Freeman et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      drprEP522/drpr[+] is a suppressor of visible | dominant phenotype of Bx1

      (Bejarano et al., 2008)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      drprEP522/drpr[+] is a suppressor of wing margin phenotype of Bx1

      (Bejarano et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      BcDNA:GH03529EP522
      drprEP(3)522
      (Freeman et al., 2003)
      drprEP522
      Name Synonyms
      Secondary FlyBase IDs
        References (5)