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General Information
Symbol
Dmel\dshUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0138246
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dsh, UAS-dsh-myc, UAS-Dsh:Myc
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of dsh tagged at the C-terminus with Tag:MYC.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of dshScer\UAS.T:Hsap\MYC driven by Scer\GAL4tap-Gal4 results in a significant increase in the frequency of mild and severe mushroom body beta lobe axon midline crossing defects (no significant effect on frequency of missing alpha lobes) compared to wild type.

Expression of dshScer\UAS.T:Hsap\MYC under the control of Scer\GAL4ap-md544 results in defects in planar polarity in the leg and the joint between tarsal segments T4 and T5 is absent.

Adults expressing dshScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF have reduced eyes. Surviving flies expressing dshScer\UAS.T:Hsap\MYC under the control of Scer\GAL469B have ectopic mechanosensory bristles near the wing margin, severe vein and planar polarity defects and in some cases have wing blisters.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of dshScer\UAS.T:Hsap\MYC does not suppress the wing notching seen when Klp64DNIG.10642R is expressed under the control of Scer\GAL4bbg-C96.

Expression of dshScer\UAS.T:Hsap\MYC under the control of Scer\GAL4ey.PH leads to an enhancement of the ventral eye loss phenotype of L2/+ flies.

Xenogenetic Interactions
Statement
Reference

Co-expression of dshScer\UAS.T:Hsap\MYC with Hsap\MAPTScer\UAS.1N4R under the control of Scer\GAL4unspecified suppresses the axonal transport defects and locomotor impairments induced by the expression of Hsap\MAPTScer\UAS.1N4R alone.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (3)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
dshScer\UAS.T:Hsap\MYC
dshUAS.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (11)