FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sesBG0247
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General Information
Symbol
Dmel\sesBG0247
Species
D. melanogaster
Name
FlyBase ID
FBal0151496
Feature type
allele
Associated gene
Dmel\sesB
Associated Insertion(s)
P{lacW}Ant2G0247
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schäfer et al., 1999.8.12)
Progenitor genotype
Associated Insertion(s)
P{lacW}Ant2G0247
Cytology
Description

The P{lacW} insertion maps within both Ant2 and sesB (transcription units with non-overlapping ORFs which share untranslated sequences).

(FlyBase, 1996-)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      FlyBase curator comment: the P{lacW} insertion results in homozygous lethality during the first and second larval instars, but since the insertion is within both the Ant2 and sesB transcription units, it is unclear whether the lethality is due to an effect on Ant2 or sesB (or both).

      (Peter et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      sesBG0247, Ant2G0247, sesB[+], Ant2[+] is a suppressor of abnormal eye color phenotype of Hsap\BCL2L13UAS.cNa, Scer\GAL4GMR.PS

      (Nakazawa et al., 2016)
      Other
      Statement
      Reference

      Ant2G0247, sesBG0247 has lethal | recessive phenotype

      (Schäfer et al., 1999.8.12)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The loss of pigment in the eye phenotype induced by expression of Hsap\BCL2L13Scer\UAS.cNa driven by Scer\GAL4GMR.PS is significantly suppressed Ant2G0247 sesBG0247/+.

      (Nakazawa et al., 2016)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} not verified as causing the lethality.

      (Schäfer et al., 1999.8.12)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      l(1)G0247
      (Peter et al., 2002)
      l(1)G0247G0247
      sesBG0247
      (Nakazawa et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0100330
      References (5)