FB2026_02 , released June 18, 2026
Allele: Dmel\spinI.UAS
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General Information
Symbol
Dmel\spinI.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0175452
Feature type
allele
Associated gene
Dmel\spin
Associated Insertion(s)
Carried in Construct
P{UAS-spin.I}
Key Links
Transgenic product class
cDNA
(Nakano et al., 2001)
wild_type
(Nakano et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Nakano et al., 2001)
wild_type
(Nakano et al., 2001)
Mutagen
in vitro construct
(Nakano et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-spin.I}
Cytology
Description

UAS regulatory sequences drive expression of the spin type I cDNA.

(Nakano et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
spin
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      spinI.UAS/Scer\GAL4spin.PN rescues spin1

      (Nakano et al., 2001)

      spinI.UAS/Scer\GAL4spin.PN rescues spin10403

      (Nakano et al., 2001)
      Partially rescues

      spinI.UAS/Scer\GAL4spin.PN partially rescues spin10403

      (Yuva-Aydemir et al., 2011)

      spinI.UAS/Scer\GAL4da.G32 partially rescues spin10403

      (Yuva-Aydemir et al., 2011)

      spinI.UAS/Scer\GAL4repo.PU partially rescues spin10403

      (Yuva-Aydemir et al., 2011)

      spinI.UAS/Scer\GAL4elav.PU partially rescues spin10403

      (Yuva-Aydemir et al., 2011)

      spinI.UAS/Scer\GAL4ey.3.5.Exel partially rescues spin10403

      (Yuva-Aydemir et al., 2011)

      spinI.UAS/Scer\GAL4c527 partially rescues spin10403

      (Yuva-Aydemir et al., 2011)

      spinI.UAS/Scer\GAL4Ntan1-Mz97 partially rescues spin10403

      (Yuva-Aydemir et al., 2011)
      Fails to rescue

      spinI.UAS/Scer\GAL4moody.SPG fails to rescue spin10403

      (Yuva-Aydemir et al., 2011)
      Comments

      spinI.Scer\UAS in the absence of a Scer\GAL4 driver can weakly rescue the eye disc defects of spin10403 larvae.

      Expression of spinI.Scer\UAS under the control of Scer\GAL4da.G32 strongly rescues the glial migration and morphology defects seen in spin10403 eye discs.

      Expression of spinI.Scer\UAS under the control of either Scer\GAL4spin.PN or Scer\GAL4repo.PU partially rescues the glial migration and morphology defects seen in spin10403 eye discs.

      Expression of spinI.Scer\UAS under the control of either Scer\GAL4elav.PU, Scer\GAL4ey.3.5.Exel, Scer\GAL4c527 or Scer\GAL4Mz97 only slightly ameliorates the glial migration and morphology defects seen in spin10403 eye discs.

      Expression of spinI.Scer\UAS under the control of Scer\GAL4moody.SPG does not significantly rescue the eye disc defects of spin10403 larvae.

      (Yuva-Aydemir et al., 2011)

      Expression of spinI.Scer\UAS under the control of Scer\GAL4spin.PN rescues the reduced receptivity of homozygous spin1 females. Expression of spinI.Scer\UAS under the control of Scer\GAL4spin.PN rescues the lethality of spin10403 homozygotes.

      (Nakano et al., 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      spinI.Scer\UAS
      spinI.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)