FlyBase Allele Report: Scer\GAL4[moody.SPG]

ScerGAL4^moody.SPG drives expression in carpet glia in the larval eye disc, in the glia between the retina and optic lamina at pupal and adult stages, and also in subperineurial glial cells of the adult brain.

(Yeh et al., 2018)

Drives expression in subperineurial, pseudocartridge, and carpet glial cells.

(FlyBase Curators, 2017)

Marker for

embryonic/larval CNS subperineurial glial cell

(Schmidt et al., 2012)

embryonic/larval carpet glial cell

(Yuva-Aydemir et al., 2011, Silies et al., 2007)

embryonic/larval subperineurial glial cell

(Pogodalla et al., 2021)

Reflects expression of

moody

(Pogodalla et al., 2021, Von Stetina et al., 2018)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior, with Hr3^JF02542

(Lama et al., 2022)

abnormal courtship behavior, with Hr3^JF02543

(Lama et al., 2022)

abnormal locomotor behavior | adult stage, with Khc^GD12278

(Schmidt et al., 2012)

abnormal neuroanatomy | adult stage, with Atg7^JF02787

(Damulewicz et al., 2022)

abnormal neuroanatomy | third instar larval stage, with Khc^GD12278

(Schmidt et al., 2012)

abnormal sleep | adult stage, with Atg7^JF02787

(Damulewicz et al., 2022)

decreased body size | larval stage, with Dhc64C^HMS01587

(Annes et al., 2026)

decreased body size | larval stage, with Khc^GL00330

(Annes et al., 2026)

decreased body size | larval stage, with klar^JF02944

(Annes et al., 2026)

decreased cell size | larval stage, with Dhc64C^HMS01587

(Annes et al., 2026)

decreased cell size | larval stage, with klar^JF02944

(Annes et al., 2026)

decreased cell size | larval stage, with koi^KK106748

(Annes et al., 2026)

decreased cell size | larval stage, with Msp300^HMS00368

(Annes et al., 2026)

decreased rate of adult locomotory behavior, with LanB1^GD13179

(Yasuda et al., 2025)

decreased rate of adult locomotory behavior, with LanB1^NIG.7123R

(Yasuda et al., 2025)

decreased size | larval stage, with Dhc64C^HMS01587

(Annes et al., 2026)

decreased size | larval stage, with ens^KK104271

(Annes et al., 2026)

decreased size | larval stage, with Khc^GL00330

(Annes et al., 2026)

decreased size | larval stage, with klar^JF02944

(Annes et al., 2026)

decreased size | larval stage, with koi^KK106748

(Annes et al., 2026)

decreased size | larval stage, with Msp300^HMS00368

(Annes et al., 2026)

decreased sleep | adult stage, with CG6126^GD1821

(Avila et al., 2025)

increased cell number, with Pvf2^d02444

(Winkler et al., 2021)

increased sleep | adult stage, with Atg7^JF02787

(Damulewicz et al., 2022)

lethal, with Lam^UAS.cGa

(Padiath et al., 2006)

lethal, with Mmp2^UAS.cPa

(Meyer et al., 2014)

lethal - all die before end of larval stage, with hid^UAS.cZa

(Silies et al., 2007)

lethal - all die before end of larval stage, with Mmp2^E258A.UAS

(Meyer et al., 2014)

lethal - all die during embryonic stage, with Df(2R)Ntan^Δ, Ntan1^UAS.cZa

(Zülbahar et al., 2018)

majority die during larval stage, with Dhc64C^HMS01587

(Annes et al., 2026)

partially lethal, with Khc^GL00330

(Annes et al., 2026)

partially lethal - majority die, with Dhc64C^HMS01587

(Annes et al., 2026)

partially lethal - majority die, with dre4^GL00017

(Ma et al., 2023)

short lived, with LanB1^GD13179

(Yasuda et al., 2025)

short lived, with LanB1^HMS02451

(Yasuda et al., 2025)

short lived, with LanB1^NIG.7123R

(Yasuda et al., 2025)

some die during larval stage, with hid^UAS.cZa

(Silies et al., 2007)

some die during larval stage, with Khc^GL00330

(Annes et al., 2026)

some die during P-stage, with Khc^GL00330

(Annes et al., 2026)

viable, with ens^KK104271

(Annes et al., 2026)

viable, with klar^JF02944

(Annes et al., 2026)

viable, with koi^KK106748

(Annes et al., 2026)

viable, with LanB1^UAS.Tag:HA

(Yasuda et al., 2025)

viable, with Msp300^HMS00368

(Annes et al., 2026)

Phenotype Manifest In

adult s-LNv neuron | adult stage, with Atg7^JF02787

(Damulewicz et al., 2022)

central nervous system, with Pvf2^d02444

(Winkler et al., 2021)

embryonic/larval carpet glial cell, with spin^RNAi.UAS.cUa

(Yuva-Aydemir et al., 2011)

embryonic/larval carpet glial cell | heat sensitive, with Scer\GAL80^ts.αTub84B, hid^UAS.cZa

(Silies et al., 2007)

embryonic/larval CNS subperineurial glial cell | third instar larval stage, with Egfr^DN.UAS.cBa

(Matzat et al., 2015)

embryonic/larval optic lobe | larval stage, with Dhc64C^HMS01587

(Annes et al., 2026)

embryonic/larval optic lobe | larval stage, with ens^KK104271

(Annes et al., 2026)

embryonic/larval optic lobe | larval stage, with Khc^GL00330

(Annes et al., 2026)

embryonic/larval optic lobe | larval stage, with klar^JF02944

(Annes et al., 2026)

embryonic/larval optic lobe | larval stage, with koi^KK106748

(Annes et al., 2026)

embryonic/larval optic lobe | larval stage, with Msp300^HMS00368

(Annes et al., 2026)

embryonic/larval subperineurial glial cell | larval stage, with Dhc64C^HMS01587

(Annes et al., 2026)

embryonic/larval subperineurial glial cell | larval stage, with ens^KK104271

(Annes et al., 2026)

embryonic/larval subperineurial glial cell | larval stage, with Khc^GL00330

(Annes et al., 2026)

embryonic/larval subperineurial glial cell | larval stage, with klar^JF02944

(Annes et al., 2026)

embryonic/larval subperineurial glial cell | larval stage, with koi^KK106748

(Annes et al., 2026)

embryonic/larval subperineurial glial cell | larval stage, with Msp300^HMS00368

(Annes et al., 2026)

glial cell | heat sensitive, with Scer\GAL80^ts.αTub84B, hid^UAS.cZa

(Silies et al., 2007)

larval peripheral nervous system | third instar larval stage, with Khc^GD12278

(Schmidt et al., 2012)

nucleus | larval stage, with Dhc64C^HMS01587

(Annes et al., 2026)

nucleus | larval stage, with ens^KK104271

(Annes et al., 2026)

nucleus | larval stage, with Khc^GL00330

(Annes et al., 2026)

nucleus | larval stage, with klar^JF02944

(Annes et al., 2026)

nucleus | larval stage, with koi^KK106748

(Annes et al., 2026)

nucleus | larval stage, with Msp300^HMS00368

(Annes et al., 2026)

plasmatocyte | increased number, with Pvf2^d02444

(Winkler et al., 2021)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Mdr65^{G1190D.UAS.GFP}/Scer\GAL4^moody.SPG rescues Mdr65^Ex8

(Mayer et al., 2009)

Fails to rescue

cold^UAS.N.Tag:HA/Scer\GAL4^moody.SPG fails to rescue cold^f05607

(Syed et al., 2011)

spin^I.UAS/Scer\GAL4^moody.SPG fails to rescue spin¹⁰⁴⁰³

(Yuva-Aydemir et al., 2011)

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

90883

w^*; P{moody-GAL4.SPG}2

602889

P{moody-GAL4.SPG}B2, w^*

602890

w^*; P{moody-GAL4.SPG}B1

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Scer\GAL4^SPG

Scer\GAL4^moody.PK

Scer\GAL4^moody.SPG

Name Synonyms

moody promoter construct of Klambt

Secondary FlyBase IDs

FBal0247683
FBal0256681

References (50)

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