CadN405 suppresses the R8 cell targeting defects seen when seqScer\UAS.cBa is expressed under the control of Scer\GAL4GMR.long. The R8 axons no longer terminate in the M6 layer of the medulla and correctly target the M3 layer. However the flies do show an R7 targeting phenotype; the R7 photoreceptors target the M3 layer rather than the M6 layer, as is seen in CadN405 mutants alone.
Expression of seqScer\UAS.cBa in the ectoderm under the control of Scer\GAL469B rescues the ganglionic branch bifurcation phenotype found in seqC022 and seqZ1241 homozygotes and seqZ1241/seqC022 trans-heterozygotes.
Expression of seqScer\UAS.cBa in midline precursors and glia of seqZ1241, seqC022 and seqZ1241/seqC022 mutants under the control of Scer\GAL4sim.PS accomplishes approximately 50% rescue with those embryos that were not fully rescued showing a considerable attenuation of the phenotype.