FB2026_02 , released June 18, 2026
Allele: Scer\GAL4upd3.PA
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General Information
Symbol
Scer\GAL4upd3.PA
Species
S. cerevisiae
Name
upd3 promoter construct of Agaisse
FlyBase ID
FBal0181583
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{upd3-GAL4.A}
Also Known As
upd3-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Agaisse et al., 2003)
Progenitor genotype
Carried in construct
P{upd3-GAL4.A}
Cytology
Description

A 4kb upd3 promoter regulates expression of a GAL4 driver.

(Agaisse et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
upd3
upd3_upd3promoter
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      hemocyte
      (Reitman et al., 2015)
      third instar larval stage
      medullary zone of lymph gland primary lobe
      (Jung et al., 2005)
      posterior signaling center of lymph gland primary lobe
      (Jung et al., 2005)
      wandering third instar larval stage
      wing hinge primordium | restricted
      (Wang et al., 2014)
      dorsal mesothoracic pleura primordium | restricted
      (Wang et al., 2014)
      wing pouch | restricted
      (Wang et al., 2014)
      embryonic/larval optic stalk
      (Wang et al., 2014)
      eye disc posterior compartment | restricted
      (Wang et al., 2014)
      adult stage
      hemocyte
      (Jung et al., 2005, Agaisse et al., 2003)
      adult proventriculus
      (Buchon et al., 2009)
      adult anal pad
      (Buchon et al., 2009)
      enterocyte
      (Osman et al., 2012)
      adult midgut region R3a
      (Guo et al., 2013)
      adult midgut region R3b
      (Guo et al., 2013)
      adult midgut region R4
      (Guo et al., 2013)
      adult midgut region R5
      (Guo et al., 2013)
      Additional Information
      Statement
      Reference

      Drives expression in hemocytes, the medullary zone and posterior signaling cener of the lymph gland primary lobe, and in midgut enterocytes.

      (FlyBase Curators, 2017)

      ScerGAL4upd3.PA drives expression in the medial fold of the wing hinge primordium, in a small region of the wing pouch, and a small domain corresponding the ventral body wall; expression does not overlap with that of upd1. ScerGAL4upd3.PA also drives expression in the embryonic/larval optic stalk, and in the posterior of the eye disc; expression is broader than that of native upd3 or upd1.

      (Wang et al., 2014)

      ScerGAL4upd3.PA drives weak expression in the copper cell region of the adult middle midgut (adult midgut regions R3a and R3b) and in part of the posterior midgut (adult midgut regions 4 and 5) under control conditions, but is more broadly detectable in midguts induced by bleomycin or bacterial infecton.

      (Guo et al., 2013)

      ScerGAL4upd3.PA drives weak expression in large-nucleated midgut enterocytes under basal conditions, but is strongly induced in flies infected with bacteria such as Ecc15.

      (Osman et al., 2012)
       
      Marker for
      Reflects expression of
      upd3
      (Reitman et al., 2015, Wang et al., 2014, Guo et al., 2013, Osman et al., 2012, Buchon et al., 2009, Jung et al., 2005, Agaisse et al., 2003)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4upd3.PA
      Name Synonyms
      upd3 promoter construct of Agaisse
      (Agaisse et al., 2003)
      Secondary FlyBase IDs
        References (26)