FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\RpL36+t4
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General Information
Symbol
Dmel\RpL36+t4
Species
D. melanogaster
Name
FlyBase ID
FBal0193398
Feature type
allele
Associated gene
Dmel\RpL36
Associated Insertion(s)
Carried in Construct
P{RpL36+t4}
Also Known As
RpL36+
Key Links
Transgenic product class
genomic_DNA
(Tyler et al., 2007)
wild_type
(Tyler et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Tyler et al., 2007)
wild_type
(Tyler et al., 2007)
Mutagen
in vitro construct
(Tyler et al., 2007)
Progenitor genotype
Carried in construct
P{RpL36+t4}
Cytology
Description

4kb BamHI genomic fragment spanning the RpL36 locus.

(Tyler et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
RpL36
Encoded product / tool
RpL36
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Df(1)su(s)R194-heterozygous clones in the larval eye disc are outcompeted by neighboring clones that also harbor one or two copies of RpL36+t4, as shown by their decreased clone size.

      (Kale et al., 2018)

      When clones of RpL36/+ (Df(1)su(s)R194/+) cells are generated in a wild-type background, making use of an RpL36+ transgene (RpL36+t4) linked to FRT80B, these cells are eliminated by cell competition.

      (Kale et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Df(1)su(s)R194, RpL36+t4 has cell lethal | somatic clone phenotype, suppressible by Df(3L)H99

      (Kale et al., 2015)
      NOT suppressed by
      Statement
      Reference

      Df(1)su(s)R194, RpL36+t4 has cell lethal | somatic clone phenotype, non-suppressible by Df(3L)IRER

      (Kale et al., 2015)

      Df(1)su(s)R194, RpL36+t4 has cell lethal | somatic clone phenotype, non-suppressible by p535A-1-4

      (Kale et al., 2015)

      Df(1)su(s)R194, RpL36+t4 has cell lethal | somatic clone phenotype, non-suppressible by DroncI29

      (Kale et al., 2015)

      Df(1)su(s)R194, RpL36+t4 has cell lethal | somatic clone phenotype, non-suppressible by DroncI24

      (Kale et al., 2015)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Df(1)su(s)R194-heterozygous clones in the larval eye disc are outcompeted by neighboring clones that also harbor RpL36+t4); this phenotype is suppressed by homozygosity for RpS12G97D alone or in combination with RpS12G97D.2kb, but not by two copies of RpS12+t2, two copies of RpS12G97D.2kb, homozygosity for RpS12s2783 alone or homozygosity for RpS12s2783 in combination with RpS12+t2.

      In RpS174 heterozygous larval wing discs, clones bearing two copies of RpL36+t4 do not compete with otherwise wild-type neighboring clones, as shown by their comparable clone size.

      (Kale et al., 2018)

      When clones of RpL36/+ (Df(1)su(s)R194/+) cells are generated in a wild-type background, making use of an RpL36+ transgene (RpL36+t4) linked to FRT80B, these cells are eliminated by cell competition. By contrast, clones of RpL36/+; Df(3L)H99/Df(3L)H99 cells survive in the imaginal discs and adult eye. Clones of RpL36/+; Df(3L)IRER/Df(3L)IRER do not survive.

      (Kale et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      RpL36+t4 rescues Df(1)su(s)R194

      (Tyler et al., 2007)
      Comments

      Rescues the Minute bristle phenotype of Df(1)su(s)R194.

      (Tyler et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      RpL36+t4
      Name Synonyms
      Secondary FlyBase IDs
        References (6)