Expression of wakeGD12087 under the control of Scer\GAL4pnr-MD237 causes defects in the establishment of polarity in sensory organ precursor (SOP) cells. Expression of wakeGD12087 causes the formation of external sensory organs that contain two neurons and two sheath cells, indicating a cell transformation of pIIa into pIIb.
Expression of wakeGD12087 in all neuroblasts under the control of Scer\GAL4insc-Mz1407 does not cause an obvious change in neuroblast numbers in the larval brain, however it does produce defects in the basal segregation of mira.
Adults expressing wakeGD12087 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4pnr-MD237 results in external sensory organs consisting of empty or multiple sockets in 0% or 10-20% of the Scer\GAL4pnr-MD237 expression domain of the notum, depending on the insertion line used.