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General Information
Symbol
Dmel\lolaKK110256
Species
D. melanogaster
Name
FlyBase ID
FBal0236738
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of lolaKK110256 under the control of Scer\GAL4GMR.PF has no effect on the adult eye morphology.

Expression of lolaKK110256 under the control of Scer\GAL4Bx-MS1096 has no effect on male wing size or patterning.

Expression of lolaKK110256 under the control of Scer\GAL4Bx-MS1096 has no effect on female wing size or patterning.

Scer\GAL4en-e16E-mediated expression results in a moderate reduction in size of the posterior compartment of the adult wing.

The expression of lolaKK110256 under the control of Scer\GAL4221, in combination with Dicer-2 for efficient RNAi, results in third instar larval class I abdominal dorsal multidendritic neurons ddaD and ddaE exhibiting a significant decrease in the number of dendrite branch terminals, as compared to controls.

Expressing lolaKK110256 under the control of Scer\GAL4ppk.PG, in combination with Dicer-2 for efficient RNAi, results in third instar larval class IV abdominal dorsal multidendritic neurons ddaC exhibiting dendrite branch terminals of similar number but of significantly lower average length, as compared to controls.

Expression of lolaKK110256 in C-I neurons under the control of Scer\GAL4221 results in ddaD neurons that have an increased number of dendritic branches compared to controls. Dendritic phenotypes are also seen in ddaE neurons. No defects are seen in vpda neurons.

Expression of lolaKK110256 in C-IV neurons under the control of Scer\GAL4ppk.1.9 results in a reduction in total dendritic length in ddaC, v'ada and vdaB neurons. The total number of dendritic branches is also reduced in ddaC and vdaB neurons.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The small eye phenotype characteristic for adult flies expressing ninaEG69D.Scer\UAS under the control of Scer\GAL4GMR.PF is enhanced further by co-expression of lolaKK110256.

The increased number of dendrite terminals in third instar larval class I abdominal dorsal multidendritic ddaD and ddaE neurons expressing knScer\UAS.cHa.T:Ivir\HA1 under the control of Scer\GAL4221 is fully suppressed by co-expressing lolaKK110256.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
lolaKK110256
Name Synonyms
Secondary FlyBase IDs
    References (7)