FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ilp31
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General Information
Symbol
Dmel\Ilp31
Species
D. melanogaster
Name
FlyBase ID
FBal0243893
Feature type
allele
Associated gene
Dmel\Ilp3
Associated Insertion(s)
TI{TI}Ilp31
Carried in Construct
Also Known As
dilp31, dilp3 KO
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
I-SceI
(Grönke et al., 2010)
FLPase
(Grönke et al., 2010)
ends-out gene targeting
(Grönke et al., 2010)
Progenitor genotype
Associated Insertion(s)
TI{TI}Ilp31
Cytology
Description

The entire Ilp3 coding sequence has been replaced by a w+mW.hs marker.

(Grönke et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Female Ilp31 flies show a significantly reduced re-mating rate 24 hours after mating to wild-type flies, compared to control flies.

      (Wigby et al., 2011)

      Ilp31 mutants are 100% viable; show no delay in egg-to-adult development time; show no reduction in adult body weight; have reduced lifetime fecundity; and have normal median lifespan, paraquat resistance, starvation resistance, and lipid, glycogen and trehalose storage levels.

      (Grönke et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Other
      Statement
      Reference

      Ilp21, Ilp31, Ilp51, foxoΔ94 has lethal phenotype

      (Slack et al., 2011)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Female Ilp31 flies do not show a significantly reduced re-mating rate 5 hours after mating to Acp70A0 flies.

      (Wigby et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      Dilp31
      (Okada et al., 2023)
      Ilp31
      (Kauffman and DiAngelo, 2024)
      Ilp3[1]
      (Cong et al., 2015)
      dilp31
      (Lv et al., 2024, Okamoto and Nishimura, 2015)
      dilp3Δ
      (Alic et al., 2011)
      ilp31
      (Zhang et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (14)