FlyBase Allele Report: Dmel\LKRSDH[MB01942]

General Information

Symbol

Dmel\LKRSDH^MB01942

Species

D. melanogaster

Name

FlyBase ID

FBal0212544

Feature type

allele

Associated gene

Dmel\LKRSDH

Associated Insertion(s)

Mi{ET1}LKRSDH^MB01942

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

Mi{ET1}LKRSDH^MB01942

Cytology

Description

Allele components

Component

Use(s)

Inserted element

Mi{ET1}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:7,794,764..7,794,764 [+]

(Lv et al., 2024, St Clair et al., 2017, Bellen, 2007.5.25)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm | adult stage | progressive

(Lv et al., 2024)

decreased rate of movement | adult stage

(Lv et al., 2024)

short lived

(Lv et al., 2024)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

LKRSDH^MB01942 has abnormal circadian rhythm | adult stage | progressive phenotype, suppressible by Ilp5⁴/Df(3L)Ilp1-4

(Lv et al., 2024)

LKRSDH^MB01942 has abnormal circadian rhythm | adult stage | progressive phenotype, suppressible by Ilp3¹/Ilp5¹

(Lv et al., 2024)

LKRSDH^MB01942 has abnormal circadian rhythm | adult stage | progressive phenotype, suppressible by Ilp2¹/Ilp2[+]

(Lv et al., 2024)

LKRSDH^MB01942 has abnormal circadian rhythm | adult stage | progressive phenotype, suppressible by Ilp5[+]/Ilp5¹

(Lv et al., 2024)

LKRSDH^MB01942 has abnormal circadian rhythm | adult stage | progressive phenotype, suppressible by Ilp3¹/Ilp3[+]

(Lv et al., 2024)

LKRSDH^MB01942 has short lived phenotype, suppressible by Ilp5⁴/Df(3L)Ilp1-4

(Lv et al., 2024)

LKRSDH^MB01942 has abnormal circadian rhythm | adult stage | progressive phenotype, suppressible | partially by Scer\GAL4^Ilp5.PU/Art4^GD5172

(Lv et al., 2024)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

LKRSDH^MB01942 is rescued by Scer\GAL4^{LKRSDH-CR70173-TG4.0}/LKRSDH^TOE.GS01508/Spyo\Cas9^UAS.cUa

(Lv et al., 2024)

Not rescued by

LKRSDH^MB01942 is not rescued by Scer\GAL4^nSyb.PP/LKRSDH^TOE.GS01508/Spyo\Cas9^UAS.cUa

(Lv et al., 2024)

LKRSDH^MB01942 is not rescued by LKRSDH^TOE.GS01508/Scer\GAL4^repo.PU/Spyo\Cas9^UAS.cUa

(Lv et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

CG7144^MB01942

(Bellen, 2007.5.25)

LKR^MB01942

LKRSDH^MB01942

(Lv et al., 2024, St Clair et al., 2017)

LKRSDH^MB

(St Clair et al., 2017)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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