FlyBase Allele Report: Scer\GAL4[lbe.K]

General Information

Symbol

Scer\GAL4^lbe.K

Species

S. cerevisiae

Name

FlyBase ID

FBal0247048

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{lbe-GAL4.K}

Also Known As

lbe(K)-Gal4, NB5-6-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Baumgardt et al., 2009)

Progenitor genotype

Carried in construct

P{lbe-GAL4.K}

Cytology

Description

The "K" enhancer fragment from the lbe gene is fused upstream of sequence encoding a GAL4 driver.

(Baumgardt et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

lbe

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 17

thoracic neuroblast NB5-6

(Karlsson et al., 2010)

abdominal neuroblast NB5-6

(Karlsson et al., 2010)

neuroblast NB5-6 of embryonic head segment

(Karlsson et al., 2010)

embryonic stage 17

apterous-expressing neuron of the lateral cluster of the thorax

(Karlsson et al., 2010)

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

neuroblast NB5-6

(Lacin and Truman, 2016)

embryonic stage 13 -- 15

thoracic neuroblast NB5-6

(Losada-Pérez et al., 2013)

apterous-expressing neuron of the lateral cluster of the thorax

(Losada-Pérez et al., 2013)

Additional Information

Statement

Reference

ScerGAL4^lbe.K is a NB5-6 lineage-specific marker.

(Karlsson et al., 2010)

Marker for

abdominal neuroblast NB5-6

(Karlsson et al., 2010)

neuroblast NB5-6

(Lacin and Truman, 2016)

thoracic neuroblast NB5-6

(Karlsson et al., 2010)

Reflects expression of

lbe

(Losada-Pérez et al., 2013)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | embryonic stage, with Fer3^UAS.Tag:HA

(Drake et al., 2025)

abnormal neuroanatomy | late embryonic stage, with kn^{UAS.cSa.Tag:HA}

(Stratmann et al., 2019)

increased cell number | embryonic stage, with Fer3^{p65AD.UAS.Tag:FLAG}

(Drake et al., 2025)

increased occurrence of cell division | embryonic stage 16, with nub^{UAS.ORF.GW.Tag:HA}

(Bahrampour et al., 2017)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

Scer\GAL4^lbe.K, kn^{UAS.cSa.Tag:HA} has abnormal neuroanatomy | late embryonic stage phenotype, non-suppressible by ap^P44/ap^P44

(Stratmann et al., 2019)

Scer\GAL4^lbe.K, kn^{UAS.cSa.Tag:HA} has abnormal neuroanatomy | late embryonic stage phenotype, non-suppressible by Df(2L)BSC354/eya^cli-IID

(Stratmann et al., 2019)

Phenotype Manifest In

NOT suppressed by

Statement

Reference

Scer\GAL4^lbe.K, kn^{UAS.cSa.Tag:HA} has abdominal neuroblast NB5-6 | late embryonic stage phenotype, non-suppressible by ap^P44/ap^P44

(Stratmann et al., 2019)

Scer\GAL4^lbe.K, kn^{UAS.cSa.Tag:HA} has abdominal neuroblast NB5-6 | late embryonic stage phenotype, non-suppressible by Df(2L)BSC354/eya^cli-IID

(Stratmann et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^lbe.K

Name Synonyms

Secondary FlyBase IDs

References (16)

Report Sections

Open Close