FlyBase Allele Report: Scer\GAL4[mir-263b-Δ-G4]

General Information

Symbol

Scer\GAL4^{mir-263b-Δ-G4}

Species

S. cerevisiae

Name

FlyBase ID

FBal0257047

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

TI{GAL4}mir-263b^Δ-G4

Carried in Construct

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

recombination

(Hilgers et al., 2010)

gene targeting by homologous recombination

(Hilgers et al., 2010)

Progenitor genotype

Associated Insertion(s)

TI{GAL4}mir-263b^Δ-G4

Cytology

Description

Sequence encoding the mir-263b miRNA hairpin has been replaced by sequence encoding a GAL4 driver and a mini-w marker. This allows for expression of GAL4 coding region under the control of the endogenous mir-263b promoter.

(Hilgers et al., 2010)

Allele components

Component

Use(s)

Inserted element

TI{GAL4}

promoter trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

pupal stage P6

interommatidial bristle

(Hilgers et al., 2010)

Additional Information

Statement

Reference

Reporter expression is detected in the shaft cells of interommatidial bristles.

(Hilgers et al., 2010)

Marker for

Reflects expression of

mir-263b

(Hilgers et al., 2010)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian behavior | adult stage, with Bx^UAS.Tag:HA

(Nian et al., 2019)

abnormal circadian behavior | adult stage, with mir-263b^UAS.cSa

(Nian et al., 2019)

abnormal circadian rhythm | adult stage, with Bx^UAS.Tag:HA

(Nian et al., 2019)

abnormal circadian rhythm | adult stage, with mir-263b^UAS.cSa

(Nian et al., 2019)

abnormal neuroanatomy | adult stage, with Bx^UAS.Tag:HA

(Nian et al., 2019)

abnormal neuroanatomy | adult stage, with mir-263b^UAS.cSa

(Nian et al., 2019)

visible, with hid^d10274

(Hilgers et al., 2010)

Phenotype Manifest In

axon collateral | adult stage, with Bx^UAS.Tag:HA

(Nian et al., 2019)

axon collateral | adult stage, with mir-263b^UAS.cSa

(Nian et al., 2019)

interommatidial bristle, with hid^d10274

(Hilgers et al., 2010)

s-LNv Pdf neuron, with Bx^UAS.Tag:HA

(Nian et al., 2019)

s-LNv Pdf neuron, with mir-263b^UAS.cSa

(Nian et al., 2019)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^{mir-263b-Δ-G4}/mir-263b^UAS.DsRed2 is a suppressor of visible phenotype of mir-bft²⁴/mir-bft^Δ263a

(Hilgers et al., 2010)

hid^GD1673/Scer\GAL4^{mir-263b-Δ-G4} is a suppressor of visible phenotype of mir-bft^unspecified/mir-bft^Δ263a

(Hilgers et al., 2010)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^{mir-263b-Δ-G4}/mir-263b^UAS.DsRed2 is a suppressor of interommatidial bristle phenotype of mir-bft²⁴/mir-bft^Δ263a

(Hilgers et al., 2010)

hid^GD1673/Scer\GAL4^{mir-263b-Δ-G4} is a suppressor of interommatidial bristle phenotype of mir-bft^unspecified/mir-bft^Δ263a

(Hilgers et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

mir-263b^UAS.cSa/Scer\GAL4^{mir-263b-Δ-G4} partially rescues mir-263b^Δ-G4/mir-263b^Δ

(Nian et al., 2019)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^{mir-263b-Δ-G4}

miR-263b-Gal4

(Hilgers et al., 2010)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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