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General Information
Symbol
Dmel\hidGD1673
Species
D. melanogaster
Name
FlyBase ID
FBal0208995
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-hid-RNAi
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adults expressing hidGD1673 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in viable flies or adult/pharate lethality.

Scer\GAL4Orct2-cald-GAL4, Scer\GAL4Kr.PM WGD1673 embryos exhibit a strong, persistent amnioserosa phenotype.

Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 0% or 90-100% of the Scer\GAL4pnr-MD237-expressing area of the notum, depending on the insertion line used.

Expression under the control of Scer\GAL4pnr-MD237 may result in an enlarged notum, depending on the insertion line used.

Expression of WGD1673 under the control of Scer\GAL4Bx-MS1096 results in crinkled wings.

Expression of WGD1673 under the control of Scer\GAL4pnr-MD237 causes a mild defective thorax closure phenotype.

External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The dendritic field coverage defects and loss of terminal branches observed in class IV dendritic arborizing neurons of third instar larvae expressing nosdsRNA.Scer\UAS.WIZ under the control of Scer\GAL4477 is suppressed by co-expression of hidGD1673 RNAi.

Expression of WGD1673 under the control of Scer\GAL4mir-263b-Δ-G4 strongly suppresses the loss of interommatidial bristles which is seen in bftΔ263a/bftunspecified flies.

RNAi-mediated knockdown of W through expression of WGD1673 under the control of Scer\GAL4GMR.PF considerably suppressed the cell death phenotype of flies expressing rprUTR.Scer\UAS.T:Ivir\HA1 in the developing eye.

Coexpression of Dcr-2Scer\UAS.cDa with WGD1673, under the control of Scer\GAL4ey.PH and Scer\GAL4GMR.PF, results in lethality, while expression of only WGD1673 with these drivers does not. Coexpression of Dcr-2Scer\UAS.cDa with WGD1673 under the control of Scer\GAL4pnr-MD237 also leads to lethality.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

RNAi-mediated knockdown of W through expression of WGD1673 in the developing eye under the control of Scer\GAL4GMR.PF suppresses WGMR.PG-induced eye ablation.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
WGD1673
hidGD1673
Name Synonyms
Secondary FlyBase IDs
    References (19)