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General Information
Symbol
Dmel\domeHMS01293
Species
D. melanogaster
Name
FlyBase ID
FBal0257888
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-DomeRNAi, dome RNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Somatic clones expressing domeHMS01293 under the control of Scer\GAL4Tub.PU contain a smaller overall number of cells and intestinal stem cells in adult flies compared to controls and show a reduction in the ratio of stem cells/clone.

The expression of domeKK104700 under the control of Scer\GAL4ci.PU leads to the non-autonomous induction of ectopic wing structures in third instar larval wing discs, as compared to controls. Expression under the control of Scer\GAL4en-e16E (and Dicer-2, for more efficient RNAi) leads to a severe size reduction of the third instar larval wing disc posterior compartment, as compared to controls.

Expression of domeHMS01293 under the control of Scer\GAL4C587 results in germaria with fewer spectrosome-containing cells, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of domeHMS01293 suppresses the increased number of spectrosomes in the germaria of flies expressing smoJF02363 under the control of Scer\GAL4C587.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The non-autonomous induction of ectopic wing structures in third instar larval wing discs resulting from the expression of domeHMS01293 under the control of Scer\GAL4ci.PU is suppressed by the co-expression of domeΔCYT.Scer\UAS.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
domeHMS01293
Name Synonyms
Secondary FlyBase IDs
    References (11)