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General Information
Symbol
Dmel\SH3PX1JF02730
Species
D. melanogaster
Name
FlyBase ID
FBal0242314
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
is ameliorated by bskGD10555
is ameliorated by domeHMS01293
is ameliorated by panΔN.UAS
is ameliorated by rhoJF03106
is ameliorated by KrnNIG.8056R
is ameliorated by stgNIG.1395R
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adulthood-only expression of SH3PX1JF02730 under the control of Scer\GAL4Su(H).GBE.cUa or Scer\GAL4esg.PU alone, or Scer\GAL4esg.PU and Scer\GAL80Su(H).GBE combined leads to a severe increase in the number of mitotic cells (phospho-H3 staining) in the adult midgut, as compared to controls; this outcome is not obtained when expression is driven by Scer\GAL4NP0001 or Scer\GAL4pros-V1. (The temporal regulation of expression is dependent on Gal80[ts] and induced by temperature shift to 29[o]C for 7 days during adulthood)

Larval fat body cells expressing SH3PX1JF02730 under the control of Scer\GAL4Act.PU show reduced production of autophagosomes compared to wild-type cells under starvation conditions.

Larval fat body cells expressing SH3PX1JF02730 under the control of Scer\GAL4Act.PU also show decreased formation of autophagic compartments in well fed 110 hour old larvae (normally undergoing developmental autophagy).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
SH3PX1JF02730
Name Synonyms
Secondary FlyBase IDs
    References (4)