FlyBase Allele Report: Scer\GAL4[VGAT.PF]

General Information

Symbol

Scer\GAL4^VGAT.PF

Species

S. cerevisiae

Name

Vesicular GABA Transporter promoter construct of Fei

FlyBase ID

FBal0263508

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{VGAT-GAL4.F}

Also Known As

vGat-Gal4, dVGAT-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Fei et al., 2010)

Progenitor genotype

Carried in construct

P{VGAT-GAL4.F}

Cytology

Description

GAL4 driver coding sequences are cloned downstream of a 6899bp 5' promoter region fragment of VGAT.

(Fei et al., 2010)

Allele components

Component

Use(s)

Regulatory region(s)

VGAT

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult insulin secreting cell of pars intercerebralis | subset

(Rajan and Perrimon, 2012)

adult brain | restricted

(Fei et al., 2010)

GABAergic neuron

(Fei et al., 2010)

Additional Information

Statement

Reference

Marker for

Reflects expression of

VGAT

(Rajan and Perrimon, 2012, Fei et al., 2010)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal optomotor response, with VGAT^MB01219, VGAT^UAS.cFa

(Fei et al., 2010)

bang sensitive, with jus^JF03192

(Horne et al., 2017)

decreased body size | adult stage, with dome^HMS00647

(Rajan and Perrimon, 2012)

decreased body size | adult stage, with Stat92E^HMS00035

(Rajan and Perrimon, 2012)

paralytic | cold sensitive, with jus^JF03192

(Dean et al., 2018)

Phenotype Manifest In

wing, with dome^HMS00647

(Rajan and Perrimon, 2012)

wing, with Stat92E^HMS00035

(Rajan and Perrimon, 2012)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^VGAT.PF/VGAT^UAS.cFa rescues VGAT^MB01219

(Fei et al., 2010)

Partially rescues

Scer\GAL4^VGAT.PF/qvr^UAS.cWa partially rescues qvr^EY04063

(Chen et al., 2015)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

58409

w^*; P{VGAT-GAL4.F}3

58980

w^*; P{VGAT-GAL4.F}2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Scer\GAL4^VGAT.PF

Scer\GAL4^VGAT

Name Synonyms

Vesicular GABA Transporter promoter construct of Fei

Secondary FlyBase IDs

References (12)

Report Sections

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