FlyBase Allele Report: Dmel\Tao[UASp.Tag:FLAG]

General Information

Symbol

Dmel\Tao^{UASp.Tag:FLAG}

Species

D. melanogaster

Name

FlyBase ID

FBal0265575

Feature type

allele

Associated gene

Dmel\Tao

Associated Insertion(s)

Carried in Construct

P{UASp-Tao.FLAG}

Key Links

Transgenic product class

wild_type

(Sato et al., 2007)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Sato et al., 2007)

Mutagen

in vitro construct

(Sato et al., 2007)

Progenitor genotype

Carried in construct

P{UASp-Tao.FLAG}

Cytology

Description

UASp regulatory sequences drive expression of Tao tagged with Tag:FLAG.

(Sato et al., 2007)

Allele components

Component

Use(s)

Regulatory region(s)

UASp

binary expression system - regulatory region

Encoded product / tool

Tao

Tagged with

Tag:FLAG

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage, with Scer\GAL4^hh.PU

(Poon et al., 2011)

abnormal size | adult stage, with Scer\GAL4^rn-GAL4-5

(Poon et al., 2011)

visible | adult stage, with Scer\GAL4^hh.PU

(Poon et al., 2011)

visible | adult stage, with Scer\GAL4^rn-GAL4-5

(Poon et al., 2011)

Phenotype Manifest In

wing | posterior, with Scer\GAL4^hh.PU

(Poon et al., 2011)

wing | posterior, with Scer\GAL4^rn-GAL4-5

(Poon et al., 2011)

Detailed Description

Statement

Reference

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} under the control of Scer\GAL4^hh.PU results in a 14% reduction in the size of the posterior compartment of the wing. Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} under the control of Scer\GAL4^rn-GAL4-5 also results in a reduction in wing size, but also produces wing scalloping.

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF does not obviously affect eye size.

(Poon et al., 2011)

The amount of pole cell apoptosis seen when Tao-1^{Scer\UAS.P\T.T:Zzzz\FLAG} is expressed under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} is comparable to controls.

(Sato et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^{VP16.nanos.UTR}, Tao^{UASp.Tag:FLAG}, nanos^BN has increased cell death | maternal effect | embryonic stage 16 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, Tao^{UASp.Tag:FLAG}, nanos^BN has increased cell death | maternal effect | embryonic stage 13 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, Tao^{UASp.Tag:FLAG}, nanos^BN has increased cell death | maternal effect | embryonic stage 14 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, Tao^{UASp.Tag:FLAG}, nanos^BN has increased cell death | maternal effect | embryonic stage 15 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Enhancer of

Statement

Reference

Tao^{UASp.Tag:FLAG}/Scer\GAL4^GMR.PF is an enhancer of visible | adult stage phenotype of sav^GMR.PT, wts^GMR.PT

(Poon et al., 2011)

Tao^{UASp.Tag:FLAG}/Scer\GAL4^GMR.PF is an enhancer of abnormal size | adult stage phenotype of sav^GMR.PT, wts^GMR.PT

(Poon et al., 2011)

Scer\GAL4^{VP16.nanos.UTR}/Tao^{UASp.Tag:FLAG} is an enhancer of increased cell death | embryonic stage 13 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}/Tao^{UASp.Tag:FLAG} is an enhancer of increased cell death | embryonic stage 14 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}/Tao^{UASp.Tag:FLAG} is an enhancer of increased cell death | embryonic stage 15 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}/Tao^{UASp.Tag:FLAG} is an enhancer of increased cell death | embryonic stage 16 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Suppressor of

Statement

Reference

Scer\GAL4^en.PU/Tao^{UASp.Tag:FLAG} is a suppressor of hyperplasia | adult stage phenotype of Scer\GAL4^en.PU, Schip1^GS12074

(Chung et al., 2016)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of abnormal size | adult stage phenotype of Scer\GAL4^en-e16E, kibra^KK111409

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of visible | adult stage phenotype of Scer\GAL4^en-e16E, kibra^KK111409

(Poon et al., 2011)

Tao^{UASp.Tag:FLAG}, Scer\GAL4^hh.PU is a suppressor of abnormal size | adult stage phenotype of Mer^NIG.14228R, Scer\GAL4^hh.PU

(Poon et al., 2011)

Tao^{UASp.Tag:FLAG}, Scer\GAL4^hh.PU is a suppressor of visible | adult stage phenotype of Mer^NIG.14228R, Scer\GAL4^hh.PU

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of abnormal size | adult stage phenotype of Scer\GAL4^en-e16E, ex^GD12782

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of visible | adult stage phenotype of Scer\GAL4^en-e16E, ex^GD12782

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of abnormal size | adult stage phenotype of Scer\GAL4^en-e16E, ft^KK101190

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of visible | adult stage phenotype of Scer\GAL4^en-e16E, ft^KK101190

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of abnormal size | adult stage phenotype of Scer\GAL4^en-e16E, dachs^{UAS.Tag:V5,Tag:polyHis}

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of visible | adult stage phenotype of Scer\GAL4^en-e16E, dachs^{UAS.Tag:V5,Tag:polyHis}

(Poon et al., 2011)

NOT Suppressor of

Statement

Reference

Tao^{UASp.Tag:FLAG}, Scer\GAL4^en-e16E is a non-suppressor of abnormal size | adult stage phenotype of Pten^{RNAi.Exel.UAS}, Scer\GAL4^en-e16E

(Poon et al., 2011)

Tao^{UASp.Tag:FLAG}, Scer\GAL4^en-e16E is a non-suppressor of visible | adult stage phenotype of Pten^{RNAi.Exel.UAS}, Scer\GAL4^en-e16E

(Poon et al., 2011)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^{VP16.nanos.UTR}, Tao^{UASp.Tag:FLAG}, nanos^BN has primordial germ cell | maternal effect | embryonic stage 13 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, Tao^{UASp.Tag:FLAG}, nanos^BN has primordial germ cell | maternal effect | embryonic stage 14 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, Tao^{UASp.Tag:FLAG}, nanos^BN has primordial germ cell | maternal effect | embryonic stage 15 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, Tao^{UASp.Tag:FLAG}, nanos^BN has primordial germ cell | maternal effect | embryonic stage 16 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Enhancer of

Statement

Reference

Tao^{UASp.Tag:FLAG}/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of sav^GMR.PT, wts^GMR.PT

(Poon et al., 2011)

Scer\GAL4^{VP16.nanos.UTR}/Tao^{UASp.Tag:FLAG} is an enhancer of primordial germ cell | embryonic stage 13 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}/Tao^{UASp.Tag:FLAG} is an enhancer of primordial germ cell | embryonic stage 14 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}/Tao^{UASp.Tag:FLAG} is an enhancer of primordial germ cell | embryonic stage 15 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}/Tao^{UASp.Tag:FLAG} is an enhancer of primordial germ cell | embryonic stage 16 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Suppressor of

Statement

Reference

Scer\GAL4^en.PU/Tao^{UASp.Tag:FLAG} is a suppressor of wing blade phenotype of Scer\GAL4^en.PU, Schip1^GS12074

(Chung et al., 2016)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of wing phenotype of Scer\GAL4^en-e16E, kibra^KK111409

(Poon et al., 2011)

Tao^{UASp.Tag:FLAG}, Scer\GAL4^hh.PU is a suppressor of wing | posterior phenotype of Mer^NIG.14228R, Scer\GAL4^hh.PU

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of wing | posterior phenotype of Scer\GAL4^en-e16E, ex^GD12782

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of wing phenotype of Scer\GAL4^en-e16E, ft^KK101190

(Poon et al., 2011)

Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG} is a suppressor of wing | posterior phenotype of Scer\GAL4^en-e16E, dachs^{UAS.Tag:V5,Tag:polyHis}

(Poon et al., 2011)

NOT Suppressor of

Statement

Reference

Tao^{UASp.Tag:FLAG}, Scer\GAL4^en-e16E is a non-suppressor of wing phenotype of Pten^{RNAi.Exel.UAS}, Scer\GAL4^en-e16E

(Poon et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} (but not Tao^{KD.Scer\UAS.T:Zzzz\FLAG}) suppresses wing changes in flies with Schip1^GS12074 driven by Scer\GAL4^en.PU.

(Chung et al., 2016)

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} reduces the wing overgrowth seen when Mer^NIG.14228R is expressed under the control of Scer\GAL4^hh.PU.

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} reduces the wing overgrowth seen when ex^GD12782 is expressed under the control of Scer\GAL4^en-e16E.

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} reduces the wing overgrowth seen when kibra^KK111409 is expressed under the control of Scer\GAL4^en-e16E.

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} reduces the wing overgrowth seen when ft^KK101190 is expressed under the control of Scer\GAL4^en-e16E.

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} reduces the wing overgrowth seen when d^{Scer\UAS.T:SV5\V5,T:Zzzz\His6} is expressed under the control of Scer\GAL4^en-e16E.

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} is unable to suppress the wing overgrowth seen when Pten^{dsRNA.Exel.Scer\UAS} is expressed under the control of Scer\GAL4^en-e16E.

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF enhances the decrease in eye size seen when wts^GMR.PT and sav^GMR.PT are co-expressed.

(Poon et al., 2011)

Expression of Tao-1^{Scer\UAS.P\T.T:Zzzz\FLAG} under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} enhances the pole cell apoptosis seen in stage 13-16 embryos derived from nos^BN females.

Removal of zygotic W (W⁰⁵⁰¹⁴/Df(3L)H99) suppresses the pole cell apoptosis seen when Tao-1^{Scer\UAS.P\T.T:Zzzz\FLAG} is expressed under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} in stage 13-16 embryos derived from nos^BN females.

(Sato et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

600535

P{UASp-Tao.FLAG}89, w^*

600533

w^*; sna^Sco/CyO, P{ActGFP}JMR1; P{UASp-Tao.FLAG}61

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Tao-1^{Scer\UAS.P\T.T:Zzzz\FLAG}

Tao^{Scer\UAS.P\T.T:Zzzz\FLAG}

Tao^{UASp.Tag:FLAG}

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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