debcl22/debclKO-unspecified flies are viable, fertile and exhibit a normal lifespan.
At variable penetrance, extra scutellar bristles are found on the notum.
debcl22/debcl27 embryos have extra Kr-positive cells in segments A4 and A5 of the ventral nerve cord - these cells normally die.
debcl22 embryos have extra Kr-positive cells in Bolwig's organ - these cells normally die.
WT and debcl22 larval wing discs show comparable increases in ionizing radiation-induced cell death.
debcl22 animals are slightly compromised for viability after ionizing radiation challenge at the larval stage.
debcl22/debcl27 and debcl22/debcl61 animals show an increased frequency of notched wings after ionizing radiation challenge at the larval stage, compared to wild type.
WT and debcl22/debcl27 larval wing discs show comparable proliferative arrest and resumption of proliferation kinetics after ionizing radiation exposure.
debcl22 and debcl22/debcl59 animals show normal starvation-induced autophagy, and normal survival curves when transferred from fed to starved conditions.