FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4Dh44
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General Information
Symbol
Scer\GAL4Dh44
Species
S. cerevisiae
Name
FlyBase ID
FBal0288510
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Dh44-GAL4.TH}
Also Known As
DH44-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Asahina and Anderson, 2013.9.23)
Progenitor genotype
Carried in construct
P{Dh44-GAL4.TH}
Cytology
Description

Putative Dh44 regulatory sequences control expression of a GAL4 driver.

(Asahina and Anderson, 2013.9.23)
Allele components
Component
Use(s)
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      Dh44 neuron
      (Okamoto and Nishimura, 2015)
      wandering third instar larval stage
      larval Dh44 neuron of pars intercerebralis
      (Hückesfeld et al., 2021)
      adult stage
      adult Dh44 neuron of pars intercerebralis
      (Zandawala et al., 2018)
      Additional Information
      Statement
      Reference

      ScerGAL4Dh44 drives expression only in a set of six Dh44-expressing neurosecretory cells of the pars intercerebralis (MNCs).

      (Zandawala et al., 2018)

      ScerGAL4Dh44 may not fully recapitulate the endogenous Dh44 expression pattern.

      (Bloomington Drosophila Stock Center, 2017)

      ScerGAL4Dh44 drives expression in Dh44-producing neurons.

      (Okamoto and Nishimura, 2015)
       
      Marker for
      Reflects expression of
      Dh44
      (Hückesfeld et al., 2021, Zandawala et al., 2018, Bloomington Drosophila Stock Center, 2017, Okamoto and Nishimura, 2015)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (via Hsap\KCNJ2UAS.EGFP) or activation (via Bhal\NaChBacUAS.EGFP) of Scer\GAL4Dh44 neurons leads to lower secretion rate of Malpighian tubules in post-injury condition.

      (Li et al., 2020)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Dop2RUAS.cDa/Scer\GAL4Dh44 fails to rescue Dop2RattP

      (Deng et al., 2019)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DH44GAL4
      (Zhao et al., 2024)
      Scer\GAL4Dh44
      Name Synonyms
      Secondary FlyBase IDs
        References (18)