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General Information
Symbol
Ecol\lexAp65.nompC
Species
E. coli
Name
FlyBase ID
FBal0291604
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
nompC-LexA, nompC-LexAp65, nompC-LexA::p65
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

nompC regulatory sequences control expression of a lexA::p65 driver. 3'UTR sequences from the Autographa californica nucleopolyhedrovirus (AcNPV) p10 gene are present downstream of the coding sequence.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Ecol\lexAp65.nompC drives expression in a subset of sensory neurons that project to the ventral side of the larval neuropil.

Ecol\lexAp65.nompC drives expression in larval multidendritic class III neurons and in larval scolopidial (chordotonal) neurons.

 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Inhibition (using Hsap\KCNJ2lexAop.cHa) of Ecol\lexAp65.nompC cells in adult females does not affect preference for softer plain, or 100 mM sucrose-containing, agarose for egg laying, compared to controls.

Optogenetic activation (using Cnoc\ChR1::Csub\ChRCsChrimson.IVS.13XLexAop2.Venus or Cnoc\ChR1::Csub\ChRlexAop.FRT.CsChrimson.Venus with 617 nm (red) light) of Ecol\lexAp65.nompC cells in adults induces labellar spread, compared to controls; there is also an induction of proboscis retraction due to stimulation during feeding, compared to controls; when activation is restricted to a subset of Ecol\lexAp65.nompC cells (using Scer\GAL4NP7506 and Scer\FLP1UAS.cUa with Cnoc\ChR1::Csub\ChRlexAop.FRT.CsChrimson.Venus), there is an induction of labellar spread, but not proboscis retraction during feeding, compared to controls; activation of this subset in the labellum also results in activation of one pair of Scer\GAL4GMR18B07-expressing motor neurons in the brain with a 2 ms delay, compared to baseline.

Inhibition (using Ctet\tetXTNT-LC.13x.lexAop.Tag:HA) of Ecol\lexAp65.nompC cells in starved adult males significantly reduces preference for softer sucrose-containing agarose, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Ecol\lexAnompC.T:Hsap\RELA
Ecol\lexAp65.nompC
Name Synonyms
Secondary FlyBase IDs
    References (15)