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General Information
Symbol
Scer\GAL4VT039046
Species
S. cerevisiae
Name
FlyBase ID
FBal0296104
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Dh44-GAL4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 2178 base pair fragment from the flanking non-coding or intronic region of Dh44 is fused upstream of a Drosophila synthetic core promoter (DSCP) followed by sequence encoding a GAL4 driver.

Allele components
Product class / Tool use(s)
Associated Sequence Features
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Axons from Scer\GAL4VT039046 expressing neurons terminate in the adult subesophageal zone with their dendritic compartments located near the pars intercerebralis and esophagus. Positive GRASP (GFP reconstitution across synaptic partners) signals between adult Hugin neurons labelled with Ecol\lexAGMR61H10 and DH44 neurons labelled with Scer\GAL4VT039046 were observed in the adult subesophageal zone, near the esophagus, and along the midline of the brain.

Scer\GAL4VT039046 drives expression in a subset of six Scer\GAL4Kurs58 positive neurons of the adult pars intercerebralis (PI) recapitulating endogenous Dh44 protein expression. GFP reconstitution across synaptic partners (GRASP) shows a connection between Scer\GAL4VT039046 positive PI neurons and Ecol\lexAClk.4.1M.T:Hsim\VP16 positive DN1p neurons.

 
Marker for
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Thermogenetic activation (using TrpA1UAS.(B).cKa at 28[o]C) of Scer\GAL4VT039046 neurons in adults results in a significant reduction in the strength of circadian locomotor rhythms, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Scer\GAL4VT039046
Name Synonyms
Secondary FlyBase IDs
    References (5)