FB2020_06, released Dec 22, 2020

Allele: Dmel\cncUAS.ORF.GW.Tag:HA

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General Information
Symbol
Dmel\cncUAS.ORF.GW.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0296929
Feature type
allele
Associated gene
Dmel\cnc
Associated Insertion(s)
Carried in Construct
M{UAS-cnc.ORF.3xHA.GW}
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Bischof and FlyORF project members, 2014.6.20)
in vitro construct - coding region fusion
(Bischof and FlyORF project members, 2014.6.20)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      M{UAS-cnc.ORF.3xHA.GW}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UAS regulatory sequences drive expression of a full-length cnc open reading frame (ORF) that is tagged at the C-terminal end with three copies of the Tag:HA epitope. The ORF is flanked by a pair of incompatible FRT sites (FRT5 and FRT2), which allows for future in vivo exchange of either the promoter or tag sequence.

      (Bischof and FlyORF project members, 2014.6.20)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UASt
      Encoded product / tool
      cnc
      Tagged with
      Tag:HA
      Also carries
      FRT2
      FRT5
      loxP
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of cncScer\UAS.ORF.GW.T:Ivir\HA1 under the control of Scer\GAL4Bx-MS1096 results in male flies with almost complete wing loss.

      Expression of cncScer\UAS.ORF.GW.T:Ivir\HA1 under the control of Scer\GAL4Bx-MS1096 results in female flies with severe wing size and patterning defects.

      (Schertel et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cncScer\UAS.ORF.GW.T:Ivir\HA1
      cncUAS.ORF.GW.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (4)