FB2026_02 , released June 18, 2026
Allele: Scer\GAL4VT040039
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General Information
Symbol
Scer\GAL4VT040039
Species
S. cerevisiae
Name
FlyBase ID
FBal0309739
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{VT040039-GAL4}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Meadows, 2015.3.13)
Progenitor genotype
Carried in construct
P{VT040039-GAL4}
Cytology
Description

A 2116 base pair fragment from the flanking non-coding or intronic region of dpr5 is fused upstream of a Drosophila synthetic core promoter (DSCP) followed by sequence encoding a GAL4 driver.

(Meadows, 2015.3.13)
Allele components
Component
Use(s)
Regulatory region(s)
VT040039
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      superior lateral protocerebrum
      (Jefferis, 2016.3.4)
      adult mushroom body alpha'-lobe
      (Jefferis, 2016.3.4)
      antennal mechanosensory and motor center
      (Jefferis, 2016.3.4)
      superior intermediate protocerebrum
      (Jefferis, 2016.3.4)
      superior medial protocerebrum
      (Jefferis, 2016.3.4)
      clamp
      (Jefferis, 2016.3.4)
      bulb
      (Jefferis, 2016.3.4)
      adult subesophageal zone
      (Jefferis, 2016.3.4)
      adult antennal lobe
      (Jefferis, 2016.3.4)
      ventrolateral protocerebrum
      (Jefferis, 2016.3.4)
      superior clamp
      (Jefferis, 2016.3.4)
      anterior optic tubercle
      (Jefferis, 2016.3.4)
      adult lateral accessory lobe
      (Jefferis, 2016.3.4)
      adult mushroom body
      (Jefferis, 2016.3.4)
      adult lateral horn
      (Jefferis, 2016.3.4)
      adult brain | restricted
      (Shuai et al., 2015)
      mushroom body extrinsic neuron
      (Shuai et al., 2015)
      mushroom body gamma lobe slice 1
      (Shuai et al., 2015)
      mushroom body gamma lobe slice 2
      (Shuai et al., 2015)
      mushroom body gamma lobe slice 3
      (Shuai et al., 2015)
      mushroom body gamma lobe slice 4
      (Shuai et al., 2015)
      mushroom body gamma lobe slice 5
      (Shuai et al., 2015)
      mushroom body beta lobe slice 1
      (Shuai et al., 2015)
      mushroom body beta lobe slice 2
      (Shuai et al., 2015)
      mushroom body beta' lobe slice 1
      (Shuai et al., 2015)
      mushroom body beta' lobe slice 2
      (Shuai et al., 2015)
      mushroom body alpha lobe slice 1
      (Shuai et al., 2015)
      dopaminergic PAM neuron 14
      (Shuai et al., 2015)
      dopaminergic PAM neuron 13
      (Shuai et al., 2015)
      Additional Information
      Statement
      Reference

      ScerGAL4VT040039 drives expression in mushroom body extrinsic neurons, including dopaminergic PAM neurons 13 and 14, that innervate mushroom body gamma lobe slices 1, 2, 3, 4, 5, mushroom body beta lobe slices 1 and 2, mushroom body beta' lobe slices 1 and 2, and mushroom body alpha lobe slice 1. Expression partially overlaps with that driven by EcollexAGMR24E12 in 12 dopaminergic PAM neurons 13 and 14.

      (Shuai et al., 2015)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Hsap\KCNJ2UAS.EGFP) of Scer\GAL4VT040039 neurons, in combination with a Gal80[ts] transgene to restrict expression to 1 day prior to training and testing, significantly improves 3 hour aversive olfactory memory, compared to controls.

      (Shuai et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4VT040039
      Name Synonyms
      Secondary FlyBase IDs
        References (2)